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    YPS5 Yps5p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852632, updated on 9-Dec-2024

    Summary

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    Official Symbol
    YPS5
    Official Full Name
    Yps5p
    Primary source
    SGD:S000003228
    Locus tag
    YGL259W
    See related
    AllianceGenome:SGD:S000003228; FungiDB:YGL259W; VEuPathDB:YGL259W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable aspartic-type endopeptidase activity. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See YPS5 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (8470..8967)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene seripauperin PAU11 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Vel1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hypo-osmotic-like stress underlies general cellular defects of aneuploidy. Tsai HJ, et al. Nature, 2019 Jun. PMID 31068692, Free PMC Article
    2. Identification and characterization of Saccharomyces cerevisiae yapsin 3, a new member of the yapsin family of aspartic proteases encoded by the YPS3 gene. Olsen V, et al. Biochem J, 1999 Apr 15. PMID 10191273, Free PMC Article
    3. Set4 regulates stress response genes and coordinates histone deacetylases within yeast subtelomeres. Jethmalani Y, et al. Life Sci Alliance, 2021 Dec. PMID 34625508, Free PMC Article
    4. A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A. Ciftci-Yilmaz S, et al. Genetics, 2018 Sep. PMID 30012561, Free PMC Article
    5. Large-scale identification of yeast integral membrane protein interactions. Miller JP, et al. Proc Natl Acad Sci U S A, 2005 Aug 23. PMID 16093310, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables aspartic-type endopeptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Yps5p
    NP_011255.1
    • Protein with similarity to GPI-anchored aspartic proteases; such proteases are Yap1p and Yap3p; mCherry fusion protein localizes to the vacuole

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      8470..8967
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181125.1 → NP_011255.1  TPA: Yps5p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011255.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VV75, P53057
      UniProtKB/TrEMBL
      B3LHV1
      Conserved Domains (1) summary
      cl11403
      Location:65 → 100
      pepsin_retropepsin_like; Cellular and retroviral pepsin-like aspartate proteases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53057.1

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