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    Cdca3 cell division cycle associated 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297594, updated on 27-Nov-2024

    Summary

    Official Symbol
    Cdca3provided by RGD
    Official Full Name
    cell division cycle associated 3provided by RGD
    Primary source
    RGD:1359093
    See related
    EnsemblRapid:ENSRNOG00000015529 AllianceGenome:RGD:1359093
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in cell division and protein ubiquitination. Predicted to be located in adherens junction. Orthologous to human CDCA3 (cell division cycle associated 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 144.5), Thymus (RPKM 129.1) and 8 other tissues See more
    Orthologs
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    Try the new Transcript table

    Genomic context

    See Cdca3 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (159321203..159325072)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (157634775..157638799)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (157347876..157351889)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486638 Neighboring gene leucine rich repeat containing 23 Neighboring gene splA/ryanodine receptor domain and SOCS box containing 2 Neighboring gene triosephosphate isomerase 1 Neighboring gene ubiquitin specific peptidase 5 Neighboring gene G protein subunit beta 3 Neighboring gene prolyl 3-hydroxylase 3 Neighboring gene uncharacterized LOC120102385

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC94266

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in adherens junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cell division cycle-associated protein 3
    Names
    TOME-1
    trigger of mitotic entry protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007648.1NP_001007649.1  cell division cycle-associated protein 3

      See identical proteins and their annotated locations for NP_001007649.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079204
      UniProtKB/Swiss-Prot
      Q68FW2
      UniProtKB/TrEMBL
      A0A8I6AGY5, A6ILL8
      Conserved Domains (1) summary
      PHA03301
      Location:476
      PHA03301; envelope glycoprotein L; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      159321203..159325072
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006237342.5XP_006237404.1  cell division cycle-associated protein 3 isoform X2

      See identical proteins and their annotated locations for XP_006237404.1

      UniProtKB/TrEMBL
      A0A8I6AGY5
      Related
      ENSRNOP00000020803.5, ENSRNOT00000020803.6
    2. XM_006237341.4XP_006237403.1  cell division cycle-associated protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006237403.1

      UniProtKB/Swiss-Prot
      Q68FW2
      UniProtKB/TrEMBL
      A0A8I6AGY5, A6ILL8
      Related
      ENSRNOP00000091987.2, ENSRNOT00000102564.2
      Conserved Domains (1) summary
      PHA03301
      Location:476
      PHA03301; envelope glycoprotein L; Provisional