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    Lenep lens epithelial protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 113917, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lenepprovided by RGD
    Official Full Name
    lens epithelial proteinprovided by RGD
    Primary source
    RGD:69433
    See related
    EnsemblRapid:ENSRNOG00000049513 AllianceGenome:RGD:69433
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Elp; Lep503
    Summary
    Orthologous to human LENEP (lens epithelial protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 50.6), Thymus (RPKM 42.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lenep in Genome Data Viewer
    Location:
    2q34
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (177117171..177117859, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (174819439..174820127, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (188727004..188727670, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene DC-STAMP domain containing 1 Neighboring gene DC-STAMP domain containing 2 Neighboring gene zinc finger and BTB domain containing 7B Neighboring gene flavin adenine dinucleotide synthetase 1 Neighboring gene CDC28 protein kinase regulatory subunit 1B Neighboring gene SHC adaptor protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A novel lens epithelium gene, LEP503, is highly conserved in different vertebrate species and is developmentally regulated in postnatal rat lens. Wen Y, et al. Exp Eye Res, 2000 Feb. PMID 10655141
    2. Lens epithelial cell mRNA. I. Cloning and sequencing of a messenger RNA with a basic motif/leucine-rich domain specifically expressed in rat lens epithelial cells. Wen Y, et al. Exp Eye Res, 1995 Jun. PMID 7641850

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    lens epithelial cell protein LEP503
    Names
    Lens epithelium 503
    lens epithelial protein 503

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053614.2 → NP_446066.2  lens epithelial cell protein LEP503

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/Swiss-Prot
      Q62699, Q9WVB7
      Related
      ENSRNOP00000065837.1, ENSRNOT00000074920.4
      Conserved Domains (1) summary
      pfam15221
      Location:1 → 61
      LEP503; Lens epithelial cell protein LEP503

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      177117171..177117859 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9WVB7.1 GenPept UniProtKB/Swiss-Prot:Q9WVB7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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