SNO4 glutathione-independent methylglyoxalase family protein [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: SNO4
Official Full Name: glutathione-independent methylglyoxalase family protein
Primary source: SGD:S000004941
Locus tag: YMR322C
See related: AllianceGenome:SGD:S000004941; FungiDB:YMR322C; VEuPathDB:YMR322C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: HSP34
Summary: Enables glyoxalase III activity. Involved in cellular response to nutrient levels. Predicted to be located in P-body. Predicted to be active in cytoplasm. Used to study Parkinson's disease and cancer. [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome XIII - NC_001145.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

protects the cell against oxidative stress and complements other stress protection systems within the cell
Title: Saccharomyces cerevisiae Hsp31p, a stress response protein conferring protection against reactive oxygen species.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables glyoxalase III activity	IBA Inferred from Biological aspect of Ancestor more info
enables glyoxalase III activity	IDA Inferred from Direct Assay more info	PubMed
enables glyoxalase III activity	IEA Inferred from Electronic Annotation more info
enables glyoxalase III activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables lyase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cellular response to nutrient levels	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in lactate biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in P-body	IEA Inferred from Electronic Annotation more info
is_active_in cellular_component	ND No biological Data available more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

NP_014055.1

Possible chaperone and cysteine protease; required for transcriptional reprogramming during the diauxic shift and for survival in stationary phase; similar to bacterial Hsp31 and yeast Hsp31p, Hsp32p, and Hsp33p; DJ-1/ThiJ/PfpI superfamily member; predicted involvement in pyridoxine metabolism; induced by mild heat stress and copper deprivation

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The following sections contain reference sequences that belong to a specific genome build. Explain