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    IMH1 Imh1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851018, updated on 3-Nov-2024

    Summary

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    Official Symbol
    IMH1
    Official Full Name
    Imh1p
    Primary source
    SGD:S000004300
    Locus tag
    YLR309C
    See related
    AllianceGenome:SGD:S000004300; FungiDB:YLR309C; VEuPathDB:YLR309C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    SYS3
    Summary
    Involved in Golgi to plasma membrane protein transport and response to endoplasmic reticulum stress. Located in Golgi apparatus and cytosol. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See IMH1 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (749034..751769, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Dpa10p Neighboring gene chitin deacetylase CDA2 Neighboring gene Ras family guanine nucleotide exchange factor CDC25 Neighboring gene Atg39p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel Golgi-localisation domain shared by a class of coiled-coil peripheral membrane proteins. Kjer-Nielsen L, et al. Curr Biol, 1999 Apr 8. PMID 10209125
    2. Mutation of the Rab6 homologue of Saccharomyces cerevisiae, YPT6, inhibits both early Golgi function and ribosome biosynthesis. Li B, et al. J Biol Chem, 1996 Jul 12. PMID 8663225
    3. Golgi recruitment of GRIP domain proteins by Arf-like GTPase 1 is regulated by Arf-like GTPase 3. Setty SR, et al. Curr Biol, 2003 Mar 4. PMID 12620188
    4. Gene expression analysis of cold and freeze stress in Baker's yeast. Rodriguez-Vargas S, et al. Appl Environ Microbiol, 2002 Jun. PMID 12039763, Free PMC Article
    5. Mechanism of action of the flippase Drs2p in modulating GTP hydrolysis of Arl1p. Hsu JW, et al. J Cell Sci, 2014 Jun 15. PMID 24706946

    See all (60) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane protein transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to endoplasmic reticulum stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Imh1p
    NP_013412.1
    • Protein involved in vesicular transport; mediates transport between an endosomal compartment and the Golgi, contains a Golgi-localization (GRIP) domain that interacts with activated Arl1p-GTP to localize Imh1p to the Golgi

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      749034..751769 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182197.2 → NP_013412.1  TPA: Imh1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013412.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VYV3, Q06704
      UniProtKB/TrEMBL
      G2WJD2, N1P1K4
      Conserved Domains (2) summary
      COG1196
      Location:42 → 746
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01465
      Location:868 → 906
      GRIP; GRIP domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06704.1

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