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    fucK L-fuculokinase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946022, updated on 3-Dec-2024

    Summary

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    Official Symbol
    fucK
    Official Full Name
    L-fuculokinase
    Primary source
    ECOCYC:EG10350
    Locus tag
    b2803
    See related
    ASAP:ABE-0009191
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2798
    Summary
    FucK can function as both an L-fucolokinase and a D-ribulokinase, the second enzyme of the L-fucose and D-arabinose degradation pathways, respectively. [More information is available at EcoCyc: EG10350].
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    Genomic context

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    Sequence:
    NC_000913.3 (2937468..2938886)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene L-fucose:H(+) symporter Neighboring gene L-fucose isomerase Neighboring gene L-fucose mutarotase Neighboring gene DNA-binding transcriptional activator FucR

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The metabolism of L-fucose. I. The purification and properties of L-fuculose kinase. HEATH EC, et al. J Biol Chem, 1962 Aug. PMID 13905785
    2. Metabolism of D-arabinose: origin of a D-ribulokinase activity in Escherichia coli. LeBlanc DJ, et al. J Bacteriol, 1971 Apr. PMID 4323967, Free PMC Article
    3. Metabolism of D-arabinose: a new pathway in Escherichia coli. LeBlanc DJ, et al. J Bacteriol, 1971 Apr. PMID 4928018, Free PMC Article
    4. An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins. Bork P, et al. Proc Natl Acad Sci U S A, 1992 Aug 15. PMID 1323828, Free PMC Article
    5. The organization of the fuc regulon specifying L-fucose dissimilation in Escherichia coli K12 as determined by gene cloning. Chen YM, et al. Mol Gen Genet, 1987 Dec. PMID 3325779

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: '98 Escherichia coli SWISS-2DPAGE database update.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-fuculokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-fuculokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-fuculokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycerol kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within D-arabinose catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in L-fucose catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within L-fucose catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in carbohydrate phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fucose catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fucose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in rhamnose catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    L-fuculokinase
    NP_417283.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2937468..2938886
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417283.2 L-fuculokinase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417283.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6M9X6V2
      Conserved Domains (1) summary
      PRK10331
      Location:3 → 472
      PRK10331; L-fuculokinase; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Other Literature Sources
    Molecular Biology Databases
    Research Materials