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    frwD putative PTS enzyme IIB component FrwD [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948452, updated on 3-Dec-2024

    Summary

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    Official Symbol
    frwD
    Official Full Name
    putative PTS enzyme IIB component FrwD
    Primary source
    ECOCYC:EG11912
    Locus tag
    b3953
    See related
    ASAP:ABE-0012941
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3944; yijN
    Summary
    frwD encodes a homolog of Enzyme IIB of the fructose-specific phosphotransferase system . frwD is not expressed when cells are grown in rich medium . [More information is available at EcoCyc: EG11912].
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    Genomic context

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    Sequence:
    NC_000913.3 (4147138..4147479)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative PTS enzyme IIB component FrwB Neighboring gene putative formate acetyltransferase 2 Neighboring gene putative pyruvate formate-lyase 2 activating enzyme PflC Neighboring gene putative DNA-binding transcriptional regulator YijO Neighboring gene phosphoethanolamine transferase EptC Neighboring gene phosphoenolpyruvate carboxylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal Structure of Hypothetical Fructose-Specific EIIB from Escherichia coli. Park J, et al. Mol Cells, 2016 Jun 30. PMID 27215198, Free PMC Article
    2. Novel phosphotransferase system genes revealed by bacterial genome analysis--a gene cluster encoding a unique Enzyme I and the proteins of a fructose-like permease system. Reizer J, et al. Microbiology (Reading), 1995 Apr. PMID 7773398
    3. High-density microarray-mediated gene expression profiling of Escherichia coli. Wei Y, et al. J Bacteriol, 2001 Jan. PMID 11133948, Free PMC Article
    4. Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes. Blattner FR, et al. Nucleic Acids Res, 1993 Nov 25. PMID 8265357, Free PMC Article
    5. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in fructose import across plasma membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transmembrane transporter complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative PTS enzyme IIB component FrwD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4147138..4147479
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418388.1 putative PTS enzyme IIB component FrwD [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418388.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AN04, A0A6N8NLE6
      Conserved Domains (1) summary
      PRK10427
      Location:1 → 113
      PRK10427; PTS fructose-like transporter subunit IIB
    Nucleotide Protein
    Heading Accession and Version

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