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    wza outer membrane polysaccharide export protein Wza [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946558, updated on 17-Dec-2024

    Summary

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    Official Symbol
    wza
    Official Full Name
    outer membrane polysaccharide export protein Wza
    Primary source
    ECOCYC:G7107
    Locus tag
    b2062
    See related
    ASAP:ABE-0006825
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2056
    Summary
    Wza function was initially inferred by analogy with strain K30; now K-12 Wza has been shown to have an identical function. [More information is available at EcoGene: EG13566]. Based on sequence similarity, Wza is a member of the outer membrane auxiliary (OMA) protein family . [More information is available at EcoCyc: G7107].
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    Genomic context

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    Sequence:
    NC_000913.3 (2136104..2137243, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein-tyrosine kinase Wzc Neighboring gene protein-tyrosine phosphatase Neighboring gene inner membrane protein YegH Neighboring gene putative assembly protein AsmA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure-function relationships of the outer membrane translocon Wza investigated by cryo-electron microscopy and mutagenesis. Ford RC, et al. J Struct Biol, 2009 May. PMID 19236919, Free PMC Article
    2. Translocation of group 1 capsular polysaccharide in Escherichia coli serotype K30. Structural and functional analysis of the outer membrane lipoprotein Wza. Nesper J, et al. J Biol Chem, 2003 Dec 12. PMID 14522970
    3. Wza: a new structural paradigm for outer membrane secretory proteins? Collins RF, et al. Trends Microbiol, 2007 Mar. PMID 17275308
    4. Crystallization and preliminary X-ray diffraction analysis of Wza outer-membrane lipoprotein from Escherichia coli serotype O9a:K30. Beis K, et al. Acta Crystallogr D Biol Crystallogr, 2004 Mar. PMID 14993692
    5. Three-dimensional structure of Wza, the protein required for translocation of group 1 capsular polysaccharide across the outer membrane of Escherichia coli. Beis K, et al. J Biol Chem, 2004 Jul 2. PMID 15090537

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables polysaccharide transmembrane transporter activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables polysaccharide transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables polysaccharide transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables porin activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within colanic acid metabolic process IGC
    Inferred from Genomic Context
    more info
    		 PubMed 
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in polysaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within polysaccharide transport EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in polysaccharide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of pore complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    outer membrane polysaccharide export protein Wza

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2136104..2137243 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416566.1 outer membrane polysaccharide export protein Wza [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416566.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AHE8, A0A7D7P453
      Conserved Domains (1) summary
      PRK15078
      Location:1 → 379
      PRK15078; polysaccharide export protein Wza; Provisional
    Nucleotide Protein
    Heading Accession and Version

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