murB UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: murB
Official Full Name: UDP-N-acetylenolpyruvoylglucosamine reductase
Primary source: ECOCYC:EG11205
Locus tag: b3972
See related: ASAP:ABE-0012999
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK3964; yijB
Summary: murB encodes the UDP-N-acetylenolpyruvoylglucosamine reductase which catalyzes the second committed step in the biosynthesis of peptidoglycan. [More information is available at EcoCyc: EG11205].
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NC_000913.3 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables FAD binding	IDA Inferred from Direct Assay more info	PubMed
enables FAD binding	IEA Inferred from Electronic Annotation more info
enables UDP-N-acetylmuramate dehydrogenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables UDP-N-acetylmuramate dehydrogenase activity	IDA Inferred from Direct Assay more info	PubMed
enables UDP-N-acetylmuramate dehydrogenase activity	IEA Inferred from Electronic Annotation more info
enables flavin adenine dinucleotide binding	IBA Inferred from Biological aspect of Ancestor more info
enables flavin adenine dinucleotide binding	IDA Inferred from Direct Assay more info	PubMed
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cell division	IEA Inferred from Electronic Annotation more info
involved_in cell wall organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell wall organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell wall organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in peptidoglycan biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within peptidoglycan biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of cell shape	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of cell shape	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed

NP_418403.1

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The following sections contain reference sequences that belong to a specific genome build. Explain