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    nlpC NlpC/P60 family lipoprotein NlpC [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946220, updated on 3-Dec-2024

    Summary

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    Official Symbol
    nlpC
    Official Full Name
    NlpC/P60 family lipoprotein NlpC
    Primary source
    ECOCYC:EG11133
    Locus tag
    b1708
    See related
    ASAP:ABE-0005704
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1706
    Summary
    First 15 aa are a type II signal peptide. spr, nlpC, yafL and ydhO are paralogs. [More information is available at EcoGene: EG11133]. The NlpC lipoprotein of Escherichia coli exhibits high sequence similarity to the p60 proteins of Listeria species and to CwlF of Bacillus subtilis . [More information is available at EcoCyc: EG11133].
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    Genomic context

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    Sequence:
    NC_000913.3 (1792267..1792731, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein adenylyltransferase SelO Neighboring gene anti-FlhDC factor RflP Neighboring gene vitamin B12 ABC transporter ATP binding subunit Neighboring gene thioredoxin/glutathione peroxidase BtuE

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of a new cell wall hydrolase gene, cwlF, which affects cell separation in Bacillus subtilis. Ishikawa S, et al. J Bacteriol, 1998 May. PMID 9573210, Free PMC Article
    2. A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map. Aiba H, et al. DNA Res, 1996 Dec 31. PMID 9097039
    3. Prediction of lipoprotein signal peptides in Gram-negative bacteria. Juncker AS, et al. Protein Sci, 2003 Aug. PMID 12876315, Free PMC Article
    4. Fine-tuning the prediction of sequences cleaved by signal peptidase II: a curated set of proven and predicted lipoproteins of Escherichia coli K-12. Gonnet P, et al. Proteomics, 2004 Jun. PMID 15174130
    5. MEROPS: the peptidase database. Rawlings ND, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381862, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in peptidoglycan turnover IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    NlpC/P60 family lipoprotein NlpC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1792267..1792731 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416223.1 NlpC/P60 family lipoprotein NlpC [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416223.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A444R0S0
      Conserved Domains (1) summary
      PRK10838
      Location:40 → 154
      spr; bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase
    Nucleotide Protein
    Heading Accession and Version

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