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    ugpA sn-glycerol 3-phosphate ABC transporter membrane subunit UgpA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947957, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ugpA
    Official Full Name
    sn-glycerol 3-phosphate ABC transporter membrane subunit UgpA
    Primary source
    ECOCYC:EG11046
    Locus tag
    b3452
    See related
    ASAP:ABE-0011272
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3436; psiB; psiC; ugp
    Summary
    Pho regulon. [More information is available at EcoGene: EG11046]. The UgpABCE glycerol-3-phosphate uptake system is a member of the ATP-Binding Cassette (ABC) Superfamily . [More information is available at EcoCyc: EG11046].
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    Genomic context

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    Sequence:
    NC_000913.3 (3590024..3590911, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF2756 domain-containing protein YhhA Neighboring gene glycerophosphodiester phosphodiesterase UgpQ Neighboring gene sn-glycerol 3-phosphate ABC transporter ATP binding subunit Neighboring gene sn-glycerol 3-phosphate ABC transporter membrane subunit UgpE Neighboring gene sn-glycerol 3-phosphate ABC transporter periplasmic binding protein Neighboring gene branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fluorouracil and the isolation of mutants lacking uridine phosphorylase in Escherichia coli: location of the gene. Pritchard RH, et al. Mol Gen Genet, 1971. PMID 4932245
    2. The structural basis of substrate translocation by the Escherichia coli glycerol-3-phosphate transporter: a member of the major facilitator superfamily. Lemieux MJ, et al. Curr Opin Struct Biol, 2004 Aug. PMID 15313233
    3. Possible involvement of the ugpA gene product in the stable maintenance of mini-F plasmid in Escherichia coli. Ezaki B, et al. Mol Gen Genet, 1990 Sep. PMID 2270076
    4. Structural comparison of lactose permease and the glycerol-3-phosphate antiporter: members of the major facilitator superfamily. Abramson J, et al. Curr Opin Struct Biol, 2004 Aug. PMID 15313234
    5. Effects of halo analogs of glycerol 3-phosphate and dihydroxyacetone phosphate upon Escherichia coli. Mildener B, et al. Antimicrob Agents Chemother, 1981 Apr. PMID 7018394, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables glycerol-3-phosphate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glycerol-3-phosphate transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables glycerophosphodiester transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within glycerol-3-phosphate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in glycerol-3-phosphate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within glycerol-3-phosphate transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within glycerophosphodiester transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of glycerol-3-phosphate-transporting ATPase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sn-glycerol 3-phosphate ABC transporter membrane subunit UgpA
    NP_417909.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3590024..3590911 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417909.1 sn-glycerol 3-phosphate ABC transporter membrane subunit UgpA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417909.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A765T388
      Conserved Domains (1) summary
      PRK10561
      Location:16 → 295
      PRK10561; sn-glycerol-3-phosphate ABC transporter permease UgpA
    Nucleotide Protein
    Heading Accession and Version

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