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    phnD phosphonate/phosphate ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948624, updated on 3-Dec-2024

    Summary

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    Official Symbol
    phnD
    Official Full Name
    phosphonate/phosphate ABC transporter periplasmic binding protein
    Primary source
    ECOCYC:EG10714
    Locus tag
    b4105
    See related
    ASAP:ABE-0013442
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4098; phn; psiD
    Summary
    Phosphonate utilization is cryptic in K-12. [More information is available at EcoGene: EG10714]. PhnD is the periplasmic binding component of the alkylphosphonate ABC transporter. [More information is available at EcoCyc: EG10714].
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    Genomic context

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    Sequence:
    NC_000913.3 (4323336..4324352, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transcriptional regulator PhnF Neighboring gene pseudo Neighboring gene phosphonate/phosphate ABC transporter ATP binding subunit Neighboring gene PF06983 family protein YjdN

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure of the Escherichia coli phosphonate binding protein PhnD and rationally optimized phosphonate biosensors. Alicea I, et al. J Mol Biol, 2011 Dec 2. PMID 22019591, Free PMC Article
    2. phnE and glpT genes enhance utilization of organophosphates in Escherichia coli K-12. Elashvili I, et al. Appl Environ Microbiol, 1998 Jul. PMID 9647836, Free PMC Article
    3. Involvement of the phosphate regulon and the psiD locus in carbon-phosphorus lyase activity of Escherichia coli K-12. Wackett LP, et al. J Bacteriol, 1987 Apr. PMID 3549702, Free PMC Article
    4. Reversible phase variation in the phnE gene, which is required for phosphonate metabolism in Escherichia coli K-12. Iqbal S, et al. J Bacteriol, 2004 Sep. PMID 15342581, Free PMC Article
    5. Sequence relationships between integral inner membrane proteins of binding protein-dependent transport systems: evolution by recurrent gene duplications. Saurin W, et al. Protein Sci, 1994 Feb. PMID 8003968, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. structural analysis of Escherichia coli phosphonate binding protein PhnD and rationally optimized phosphonate biosensors
      Title: Structure of the Escherichia coli phosphonate binding protein PhnD and rationally optimized phosphonate biosensors.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in organic phosphonate transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    phosphonate/phosphate ABC transporter periplasmic binding protein
    NP_418529.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4323336..4324352 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418529.1 phosphonate/phosphate ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418529.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7TST9
      Conserved Domains (1) summary
      cd13575
      Location:28 → 284
      PBP2_PnhD; Substrate binding domain of ABC-type phosphonate uptake system; contains the type 2 periplasmic binding fold
    Nucleotide Protein
    Heading Accession and Version

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