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    betI DNA-binding transcriptional repressor BetI [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944981, updated on 17-Dec-2024

    Summary

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    Official Symbol
    betI
    Official Full Name
    DNA-binding transcriptional repressor BetI
    Primary source
    ECOCYC:EG10111
    Locus tag
    b0313
    See related
    ASAP:ABE-0001076
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0311
    Summary
    TetR family. [More information is available at EcoGene: EG10111].
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    Genomic context

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    Sequence:
    NC_000913.3 (328747..329334, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene choline dehydrogenase Neighboring gene betaine aldehyde dehydrogenase Neighboring gene choline:H(+) symporter Neighboring gene protein YahV

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and function of negative feedback loops at the interface of genetic and metabolic networks. Krishna S, et al. Nucleic Acids Res, 2006. PMID 16684993, Free PMC Article
    2. DNA-binding properties of the BetI repressor protein of Escherichia coli: the inducer choline stimulates BetI-DNA complex formation. Rkenes TP, et al. J Bacteriol, 1996 Mar. PMID 8626295, Free PMC Article
    3. The complex bet promoters of Escherichia coli: regulation by oxygen (ArcA), choline (BetI), and osmotic stress. Lamark T, et al. J Bacteriol, 1996 Mar. PMID 8626294, Free PMC Article
    4. DNA sequence and analysis of the bet genes encoding the osmoregulatory choline-glycine betaine pathway of Escherichia coli. Lamark T, et al. Mol Microbiol, 1991 May. PMID 1956285
    5. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycine betaine biosynthetic process from choline IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within response to osmotic stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-binding transcriptional repressor BetI

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      328747..329334 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414847.3 DNA-binding transcriptional repressor BetI [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414847.3

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6N0IHR2, A0A8S7EIB1
      Conserved Domains (1) summary
      PRK00767
      Location:1 → 194
      PRK00767; transcriptional regulator BetI; Validated
    Nucleotide Protein
    Heading Accession and Version

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