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    yajR putative transport protein YajR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945058, updated on 3-Dec-2024

    Summary

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    Official Symbol
    yajR
    Official Full Name
    putative transport protein YajR
    Primary source
    ECOCYC:G6241
    Locus tag
    b0427
    See related
    ASAP:ABE-0001481
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0421
    Summary
    Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG13614]. The YajR protein is an uncharacterised member of the major facilitator superfamily (MFS) of transporters . [More information is available at EcoCyc: G6241].
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    Genomic context

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    Sequence:
    NC_000913.3 (445302..446666, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein/nucleic acid deglycase 3 Neighboring gene 2-dehydropantoate 2-reductase Neighboring gene nucleotide binding protein YajQ Neighboring gene heme O synthase Neighboring gene cytochrome bo3 subunit 4 Neighboring gene cytochrome bo3 subunit 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A. Jiang D, et al. Proc Natl Acad Sci U S A, 2013 Sep 3. PMID 23950222, Free PMC Article
    2. Analysis of a complete library of putative drug transporter genes in Escherichia coli. Nishino K, et al. J Bacteriol, 2001 Oct. PMID 11566977, Free PMC Article
    3. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212
    4. The major facilitator superfamily. Saier MH Jr, et al. J Mol Microbiol Biotechnol, 1999 Nov. PMID 10943556
    5. A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. Marger MD, et al. Trends Biochem Sci, 1993 Jan. PMID 8438231

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transmembrane transport ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative transport protein YajR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      445302..446666 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414961.4 putative transport protein YajR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414961.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1X3JLI0
      Conserved Domains (1) summary
      cd17472
      Location:17 → 389
      MFS_YajR_like; Escherichia coli inner membrane transport protein YajR and similar multidrug-efflux transporters of the Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version

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