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    nrfD putative menaquinol-cytochrome c reductase subunit NrfD [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948580, updated on 3-Dec-2024

    Summary

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    Official Symbol
    nrfD
    Official Full Name
    putative menaquinol-cytochrome c reductase subunit NrfD
    Primary source
    ECOCYC:EG11947
    Locus tag
    b4073
    See related
    ASAP:ABE-0013348
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4066; yjcK
    Summary
    The nrfD gene encodes a transmembrane protein that is part of the nitrite reductase reaction and it may transfer electrons from the quinone pool to the c-type cytochromes or it may be an adapter that enables formate dehydrogenase H to transfer electrons into an electrogenic electron-transfer chain. [More information is available at EcoCyc: EG11947].
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    Genomic context

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    Sequence:
    NC_000913.3 (4290476..4291432)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene cytochrome c552 nitrite reductase Neighboring gene periplasmic nitrite reductase penta-heme c-type cytochrome Neighboring gene putative menaquinol-cytochrome c reductase 4Fe-4S subunit Neighboring gene putative cytochrome c-type biogenesis protein NrfE Neighboring gene putative formate-dependent nitrite reductase complex subunit NrfF Neighboring gene putative formate-dependent nitrite reductase complex subunit NrfG

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of a conserved glutamine residue in tuning the catalytic activity of Escherichia coli cytochrome c nitrite reductase. Clarke TA, et al. Biochemistry, 2008 Mar 25. PMID 18311941
    2. The nitric oxide reductase activity of cytochrome c nitrite reductase from Escherichia coli. van Wonderen JH, et al. J Biol Chem, 2008 Apr 11. PMID 18245085
    3. Respiratory detoxification of nitric oxide by the cytochrome c nitrite reductase of Escherichia coli. Poock SR, et al. J Biol Chem, 2002 Jun 28. PMID 11960983
    4. Structure and spectroscopy of the periplasmic cytochrome c nitrite reductase from Escherichia coli. Bamford VA, et al. Biochemistry, 2002 Mar 5. PMID 11863430
    5. Identification of the formate dehydrogenases and genetic determinants of formate-dependent nitrite reduction by Escherichia coli K12. Darwin A, et al. J Gen Microbiol, 1993 Aug. PMID 8409924

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    acts_upstream_of_or_within anaerobic electron transport chain RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative menaquinol-cytochrome c reductase subunit NrfD
    NP_418497.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4290476..4291432
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418497.1 putative menaquinol-cytochrome c reductase subunit NrfD [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418497.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A377DYV9
      Conserved Domains (1) summary
      TIGR03148
      Location:5 → 318
      cyt_nit_nrfD; cytochrome c nitrite reductase, NrfD subunit
    Nucleotide Protein
    Heading Accession and Version

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