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    hcaC putative 3-phenylpropionate/cinnamate dioxygenase ferredoxin subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947015, updated on 3-Dec-2024

    Summary

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    Official Symbol
    hcaC
    Official Full Name
    putative 3-phenylpropionate/cinnamate dioxygenase ferredoxin subunit
    Primary source
    ECOCYC:G7334
    Locus tag
    b2540
    See related
    ASAP:ABE-0008359
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2537; hcaa3; phdB; yfhW
    Summary
    Hydrocinnamic acid is a synonym for 3-phenylpropionic acid. [More information is available at EcoGene: EG13458]. Based on sequence similarity, HcaC is thought to encode the ferredoxin component of the 3-phenylpropionate dioxygenase system . [More information is available at EcoCyc: G7334].
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    Genomic context

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    Sequence:
    NC_000913.3 (2670908..2671228)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein IroK Neighboring gene DNA-binding transcriptional dual regulator HcaR Neighboring gene putative 3-phenylpropionate/cinnamate dioxygenase subunit alpha Neighboring gene putative 3-phenylpropionate/cinnamate dioxygenase subunit beta Neighboring gene 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase Neighboring gene putative 3-phenylpropionate/cinnamate dioxygenase ferredoxin reductase subunit Neighboring gene putative inner membrane protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. 3-phenylpropionate catabolism and the Escherichia coli oxidative stress response. Turlin E, et al. Res Microbiol, 2005 Apr. PMID 15808934
    2. Isolation and characterization of Escherichia coli mutants defective for phenylpropionate degradation. Burlingame RP, et al. J Bacteriol, 1986 Oct. PMID 3531186, Free PMC Article
    3. Characterization of the recombinant Rieske [2Fe-2S] proteins HcaC and YeaW from E. coli. Boxhammer S, et al. Biometals, 2008 Aug. PMID 18286376
    4. Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12. Díaz E, et al. J Bacteriol, 1998 Jun. PMID 9603882, Free PMC Article
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 2 iron, 2 sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 2 iron, 2 sulfur cluster binding ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    enables 3-phenylpropionate dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron-sulfur cluster binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in 3-phenylpropionate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within 3-phenylpropionate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in 3-phenylpropionate catabolic process NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 3-phenylpropionate dioxygenase complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative 3-phenylpropionate/cinnamate dioxygenase ferredoxin subunit
    NP_417035.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2670908..2671228
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417035.1 putative 3-phenylpropionate/cinnamate dioxygenase ferredoxin subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417035.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A836NCQ4
      Conserved Domains (1) summary
      PRK09965
      Location:1 → 106
      PRK09965; 3-phenylpropionate dioxygenase ferredoxin subunit; Provisional
    Nucleotide Protein
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