pdxA 4-hydroxythreonine-4-phosphate dehydrogenase [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Official Symbol: pdxA
Official Full Name: 4-hydroxythreonine-4-phosphate dehydrogenase
Primary source: ECOCYC:EG10691
Locus tag: b0052
See related: ASAP:ABE-0000178
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK0053
Summary: Converts 4-hydroxy-L-threonine phosphate (HTP) to 3-amino-2-oxopropyl phosphate. [More information is available at EcoGene: EG10691]. The crystal structure of PdxA has been solved at 1.96 A resolution. [More information is available at EcoCyc: EG10691].
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NC_000913.3 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables 4-hydroxythreonine-4-phosphate dehydrogenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 4-hydroxythreonine-4-phosphate dehydrogenase activity	IDA Inferred from Direct Assay more info	PubMed
enables 4-hydroxythreonine-4-phosphate dehydrogenase activity	IEA Inferred from Electronic Annotation more info
enables NAD binding	IEA Inferred from Electronic Annotation more info
enables cobalt ion binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables protein homodimerization activity	IDA Inferred from Direct Assay more info	PubMed
enables zinc ion binding	IDA Inferred from Direct Assay more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in pyridoxal phosphate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in pyridoxal phosphate biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within pyridoxal phosphate biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in pyridoxine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in pyridoxine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within pyridoxine biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

NP_414594.1

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The following sections contain reference sequences that belong to a specific genome build. Explain