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    wcaL putative colanic acid biosynthesis glycosyl transferase WcaL [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946565, updated on 3-Dec-2024

    Summary

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    Official Symbol
    wcaL
    Official Full Name
    putative colanic acid biosynthesis glycosyl transferase WcaL
    Primary source
    ECOCYC:G7095
    Locus tag
    b2044
    See related
    ASAP:ABE-0006777
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2038; yefL
    Summary
    WcaL is believed to be a glycosyl transferase involved in colanic acid synthesis based on sequence similarity and its presence in a putative colanic acid synthesis operon . [More information is available at EcoCyc: G7095].
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    Genomic context

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    Sequence:
    NC_000913.3 (2115907..2117127, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene UTP:glucose-1-phosphate uridylyltransferase, low activity Neighboring gene putative colanic acid biosynthesis protein WcaM Neighboring gene colanic acid biosynthesis pyruvyl transferase WcaK Neighboring gene colanic acid repeat unit flippase Neighboring gene UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biosynthesis and assembly of capsular polysaccharides in Escherichia coli. Whitfield C. Annu Rev Biochem, 2006. PMID 16756484
    2. Development of a biofilm production-deficient Escherichia coli strain as a host for biotechnological applications. Sung BH, et al. Appl Environ Microbiol, 2006 May. PMID 16672475, Free PMC Article
    3. Genome-wide analyses revealing a signaling network of the RcsC-YojN-RcsB phosphorelay system in Escherichia coli. Hagiwara D, et al. J Bacteriol, 2003 Oct. PMID 13129944, Free PMC Article
    4. A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map. Itoh T, et al. DNA Res, 1996 Dec 31. PMID 9097040
    5. Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid. Stevenson G, et al. J Bacteriol, 1996 Aug. PMID 8759852, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within colanic acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in lipopolysaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in slime layer polysaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative colanic acid biosynthesis glycosyl transferase WcaL

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2115907..2117127 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416548.1 putative colanic acid biosynthesis glycosyl transferase WcaL [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416548.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7EEF7
      Conserved Domains (1) summary
      PRK15427
      Location:1 → 406
      PRK15427; colanic acid biosynthesis glycosyltransferase WcaL; Provisional
    Nucleotide Protein
    Heading Accession and Version

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