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    pliG inhibitor of g-type lysozyme [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946963, updated on 17-Dec-2024

    Summary

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    Official Symbol
    pliG
    Official Full Name
    inhibitor of g-type lysozyme
    Primary source
    ECOCYC:G6615
    Locus tag
    b1178
    See related
    ASAP:ABE-0003948
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1166; ycgK
    Summary
    First 22 aa are predicted to be a type I signal peptide. [More information is available at EcoGene: EG13892]. Targeting of YcgK to the Sec-translocase for transport across the inner membrane is SecB-dependent . [More information is available at EcoCyc: G6615].
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    Genomic context

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    Sequence:
    NC_000913.3 (1227071..1227472, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene Z-ring positioning protein MinC Neighboring gene PF05666 family protein YcgJ Neighboring gene protein YmgN Neighboring gene PF05166 family protein YcgL Neighboring gene putative isomerase/hydrolase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural and mechanistic basis of zinc regulation across the E. coli Zur regulon. Gilston BA, et al. PLoS Biol, 2014 Nov. PMID 25369000, Free PMC Article
    2. Identification of a bacterial inhibitor against g-type lysozyme. Vanderkelen L, et al. Cell Mol Life Sci, 2011 Mar. PMID 20734102, Free PMC Article
    3. Defining the role of the Escherichia coli chaperone SecB using comparative proteomics. Baars L, et al. J Biol Chem, 2006 Apr 14. PMID 16352602
    4. Comparison of the PhoPQ regulon in Escherichia coli and Salmonella typhimurium. Monsieurs P, et al. J Mol Evol, 2005 Apr. PMID 15883881
    5. BOMP: a program to predict integral beta-barrel outer membrane proteins encoded within genomes of Gram-negative bacteria. Berven FS, et al. Nucleic Acids Res, 2004 Jul 1. PMID 15215418, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. directly regulated by Zur in a zinc responsive manner
      Title: Structural and mechanistic basis of zinc regulation across the E. coli Zur regulon.
    2. a novel Escherichia coli inhibitor specific for goose (g-) type lysozymes, designated PliG (periplasmic lysozyme inhibitor of g-type lysozyme) was discovered.
      Title: Identification of a bacterial inhibitor against g-type lysozyme.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables lysozyme inhibitor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in outer membrane-bounded periplasmic space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    inhibitor of g-type lysozyme

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1227071..1227472 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415696.1 inhibitor of g-type lysozyme [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415696.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      W1X8M7
      Conserved Domains (1) summary
      pfam04151
      Location:48 → 111
      PPC; Bacterial pre-peptidase C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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