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    btsS high-affinity pyruvate receptor [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 949027, updated on 3-Dec-2024

    Summary

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    Official Symbol
    btsS
    Official Full Name
    high-affinity pyruvate receptor
    Primary source
    ECOCYC:EG12007
    Locus tag
    b2126
    See related
    ASAP:ABE-0007027
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2118; yehU
    Summary
    YehU is an inner membrane protein with six predicted transmembrane domains. [More information is available at EcoCyc: EG12007].
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    Genomic context

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    Sequence:
    NC_000913.3 (2212959..2214644, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF1307 domain-containing lipoprotein YehR Neighboring gene DUF1456 domain-containing protein YehS Neighboring gene DNA-binding transcriptional dual regulator BtsR Neighboring gene DNA-binding transcriptional activator MlrA Neighboring gene UPF0387 family protein YohO Neighboring gene glycine betaine ABC transporter membrane subunit YehW

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Single-Cell View of the BtsSR/YpdAB Pyruvate Sensing Network in Escherichia coli and Its Biological Relevance. Vilhena C, et al. J Bacteriol, 2018 Jan 1. PMID 29038258, Free PMC Article
    2. Phenotype microarray analysis of Escherichia coli K-12 mutants with deletions of all two-component systems. Zhou L, et al. J Bacteriol, 2003 Aug. PMID 12897016, Free PMC Article
    3. Transcriptome analysis of all two-component regulatory system mutants of Escherichia coli K-12. Oshima T, et al. Mol Microbiol, 2002 Oct. PMID 12366850
    4. Application of comparative genomics in the identification and analysis of novel families of membrane-associated receptors in bacteria. Anantharaman V, et al. BMC Genomics, 2003 Aug 12. PMID 12914674, Free PMC Article
    5. Identification of a High-Affinity Pyruvate Receptor in Escherichia coli. Behr S, et al. Sci Rep, 2017 May 3. PMID 28469239, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. findings suggest that the BtsS/BtsR and YpdA/YpdB network contributes to a balancing of the physiological state of all cells within a population
      Title: A Single-Cell View of the BtsSR/YpdAB Pyruvate Sensing Network in Escherichia coli and Its Biological Relevance.
    2. It is suggested that YehU/YehT participates in the stationary-phase control network.
      Title: First insights into the unexplored two-component system YehU/YehT in Escherichia coli.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monocarboxylic acid binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphorelay sensor kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphorelay signal transduction system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to nutrient levels IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    high-affinity pyruvate receptor
    NP_416630.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2212959..2214644 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416630.1 high-affinity pyruvate receptor [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416630.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376P8I3
      Conserved Domains (1) summary
      COG3275
      Location:3 → 561
      LytS; Sensor histidine kinase, LytS/YehU family [Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version

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