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    CNMa CNMamide [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38242, updated on 17-Dec-2024

    Summary

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    Official Symbol
    CNMaprovided by FlyBase
    Official Full Name
    CNMamideprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035282
    Locus tag
    Dmel_CG13936
    See related
    AllianceGenome:FB:FBgn0035282
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13936; Dmel\CG13936
    Summary
    Enables neuropeptide hormone activity. Involved in G protein-coupled receptor signaling pathway. Predicted to be located in extracellular space. Is expressed in CNMamide neurons; DN1p neurons; adult brain; and adult ventral nerve cord. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

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    See CNMa in Genome Data Viewer
    Location:
    62B7-62B7; 3-1.0 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1850915..1855591, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1850915..1855591, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Cuticular protein 62Bb Neighboring gene Cuticular protein 62Bc Neighboring gene uncharacterized protein Neighboring gene Rap1 GTPase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Glutamine enhances sucrose taste through a gut microbiota-gut-brain axis in Drosophila. Li SS, et al. Life Sci, 2024 Feb 15. PMID 38218533
    2. CNMa-CNMa receptor at microbiome-gut-brain axis: novel target to regulate feeding decision. Peng L, et al. Signal Transduct Target Ther, 2021 Jul 25. PMID 34305136, Free PMC Article
    3. Identification of a novel insect neuropeptide, CNMa and its receptor. Jung SH, et al. FEBS Lett, 2014 Jun 5. PMID 24796791
    4. Response of the microbiome-gut-brain axis in Drosophila to amino acid deficit. Kim B, et al. Nature, 2021 May. PMID 33953396
    5. The neuropeptide allatostatin C from clock-associated DN1p neurons generates the circadian rhythm for oogenesis. Zhang C, et al. Proc Natl Acad Sci U S A, 2021 Jan 26. PMID 33479181, Free PMC Article

    See all (49) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CNMa-CNMa receptor at microbiome-gut-brain axis: novel target to regulate feeding decision.
      Title: CNMa-CNMa receptor at microbiome-gut-brain axis: novel target to regulate feeding decision.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables neuropeptide hormone activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IC
    Inferred by Curator
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CNMamide
    Names
    CG13936-PB
    CG13936-PC
    CG13936-PD
    CNMa-PB
    CNMa-PC
    CNMa-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1850915..1855591 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202092.1 → NP_001189021.1  CNMamide, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189021.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C4XVK3, Q4V5Y1, Q9W076

    2. NM_001274365.1 → NP_001261294.1  CNMamide, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261294.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PE91, Q4V5Y1

    3. NM_139412.2 → NP_647669.2  CNMamide, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647669.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      C4XVK3, Q4V5Y1, Q9W076
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PE91 M9PE91
    Q9W076 Q9W076

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