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    Fam171a2 family with sequence similarity 171, member A2 [ Mus musculus (house mouse) ]

    Gene ID: 217219, updated on 16-Dec-2024

    Summary

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    Official Symbol
    Fam171a2provided by MGI
    Official Full Name
    family with sequence similarity 171, member A2provided by MGI
    Primary source
    MGI:MGI:2448496
    See related
    Ensembl:ENSMUSG00000034685 AllianceGenome:MGI:2448496
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be located in membrane. Orthologous to human FAM171A2 (family with sequence similarity 171 member A2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in whole brain E14.5 (RPKM 63.7), CNS E18 (RPKM 59.6) and 16 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam171a2 in Genome Data Viewer
    Location:
    11 D; 11 66.29 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (102327807..102338551, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (102436981..102447677, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5282 Neighboring gene solute carrier family 25, member 39 Neighboring gene STARR-seq mESC enhancer starr_30808 Neighboring gene microRNA 6930 Neighboring gene STARR-positive B cell enhancers ABC_E9375 and ABC_E8457 Neighboring gene granulin Neighboring gene integrin alpha 2b Neighboring gene STARR-positive B cell enhancer ABC_E7070 Neighboring gene G patch domain containing 8 Neighboring gene cytochrome b-c1 complex subunit 10 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Li J, et al. Nat Neurosci, 2017 Aug. PMID 28671696, Free PMC Article
    2. Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies. Murtaza N, et al. Cell Rep, 2022 Nov 22. PMID 36417873
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM171A2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199200.2 → NP_954670.2  protein FAM171A2 precursor

      See identical proteins and their annotated locations for NP_954670.2

      Status: VALIDATED

      Source sequence(s)
      AL596258, CB182176, CB202938, CJ162493
      Consensus CDS
      CCDS36344.1
      UniProtKB/Swiss-Prot
      A2A699, B7ZC48, Q05CH6, Q6P2L1
      Related
      ENSMUSP00000038486.5, ENSMUST00000049057.5
      Conserved Domains (1) summary
      pfam10577
      Location:41 → 820
      UPF0560; uncharacterized protein family UPF0560

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      102327807..102338551 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006533049.5 → XP_006533112.1  protein FAM171A2 isoform X1

      Conserved Domains (1) summary
      pfam10577
      Location:41 → 813
      UPF0560; Uncharacterized protein family UPF0560
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2A699.1 GenPept UniProtKB/Swiss-Prot:A2A699

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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