Snu13 SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5) [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Snu13provided by MGI
Official Full Name: SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)provided by MGI
Primary source: MGI:MGI:893586
See related: Ensembl:ENSMUSG00000063480 AllianceGenome:MGI:893586
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: FA-1; Fta1; Ssfa1; Nhp2l1
Summary: Enables box C/D sno(s)RNA binding activity. Involved in box C/D snoRNP assembly. Acts upstream of or within single fertilization. Part of box C/D methylation guide snoRNP complex. Is expressed in head. Orthologous to human SNU13 (small nuclear ribonucleoprotein 13). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in liver E14.5 (RPKM 88.8), liver E14 (RPKM 82.9) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 15 E1; 15 38.38 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (81925546..81931799, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (82041345..82047598, complement)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ATPase binding	ISO Inferred from Sequence Orthology more info
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables U4atac snRNA binding	ISO Inferred from Sequence Orthology more info
enables U4atac snRNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables box C/D sno(s)RNA binding	IMP Inferred from Mutant Phenotype more info	PubMed
contributes_to snoRNA binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in box C/D snoRNP assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info
involved_in mRNA splicing, via spliceosome	ISO Inferred from Sequence Orthology more info
involved_in mRNA splicing, via spliceosome	ISS Inferred from Sequence or Structural Similarity more info
involved_in maturation of SSU-rRNA	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosomal small subunit biogenesis	ISO Inferred from Sequence Orthology more info
involved_in ribosomal small subunit biogenesis	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within single fertilization	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
part_of U2-type precatalytic spliceosome	ISO Inferred from Sequence Orthology more info
part_of U2-type precatalytic spliceosome	ISS Inferred from Sequence or Structural Similarity more info
part_of U4/U6 x U5 tri-snRNP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of U4/U6 x U5 tri-snRNP complex	ISO Inferred from Sequence Orthology more info
part_of U4/U6 x U5 tri-snRNP complex	ISS Inferred from Sequence or Structural Similarity more info
part_of U4atac snRNP	ISO Inferred from Sequence Orthology more info
part_of U4atac snRNP	ISS Inferred from Sequence or Structural Similarity more info
part_of box C/D methylation guide snoRNP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of box C/D methylation guide snoRNP complex	IMP Inferred from Mutant Phenotype more info	PubMed
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of precatalytic spliceosome	IBA Inferred from Biological aspect of Ancestor more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info
part_of small-subunit processome	IBA Inferred from Biological aspect of Ancestor more info
part_of small-subunit processome	ISO Inferred from Sequence Orthology more info
part_of small-subunit processome	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: NHP2-like protein 1

Names: NHP2 non-histone chromosome protein 2-like 1; U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 tri-snRNP 15.5 kDa protein; fertilization antigen-1; high mobility group-like nuclear protein 2 homolog 1; sperm specific antigen 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.