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    Pbld2 phenazine biosynthesis-like protein domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 67307, updated on 3-Dec-2024

    Summary

    Official Symbol
    Pbld2provided by MGI
    Official Full Name
    phenazine biosynthesis-like protein domain containing 2provided by MGI
    Primary source
    MGI:MGI:1914557
    See related
    Ensembl:ENSMUSG00000020072 AllianceGenome:MGI:1914557
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mawbp; 3110049J23Rik
    Summary
    Predicted to enable identical protein binding activity and isomerase activity. Predicted to be involved in maintenance of gastrointestinal epithelium. Predicted to act upstream of or within with a positive effect on negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be active in cytoplasm. Is expressed in pancreas epithelium and renal calyx. Orthologous to human PBLD (phenazine biosynthesis like protein domain containing). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in liver adult (RPKM 25.9), large intestine adult (RPKM 8.4) and 6 other tissues See more
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    Genomic context

    See Pbld2 in Genome Data Viewer
    Location:
    10 B4; 10 32.52 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (62858319..62894592)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (63024053..63058813)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:62409633-62409742 Neighboring gene DNA replication helicase/nuclease 2 Neighboring gene RUN and FYVE domain-containing 2 Neighboring gene STARR-seq mESC enhancer starr_26916 Neighboring gene heterogeneous nuclear ribonucleoprotein H3 Neighboring gene predicted gene 16143 Neighboring gene phenazine biosynthesis-like protein domain containing 1 Neighboring gene atonal bHLH transcription factor 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    phenazine biosynthesis-like domain-containing protein 2
    Names
    MAWD binding protein homolog 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001405744.1NP_001392673.1  phenazine biosynthesis-like domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AC113107
      UniProtKB/Swiss-Prot
      Q9CXN7, Q9D2W4
      UniProtKB/TrEMBL
      K3W4L7
    2. NM_001405745.1NP_001392674.1  phenazine biosynthesis-like domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AC113107
      UniProtKB/Swiss-Prot
      Q9CXN7, Q9D2W4
      UniProtKB/TrEMBL
      K3W4L7
    3. NM_001405746.1NP_001392675.1  phenazine biosynthesis-like domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AC113107
      UniProtKB/Swiss-Prot
      Q9CXN7, Q9D2W4
      UniProtKB/TrEMBL
      K3W4L7
    4. NM_026085.3NP_080361.1  phenazine biosynthesis-like domain-containing protein 2

      See identical proteins and their annotated locations for NP_080361.1

      Status: VALIDATED

      Source sequence(s)
      AC113107
      Consensus CDS
      CCDS23894.1
      UniProtKB/Swiss-Prot
      Q9CXN7, Q9D2W4
      UniProtKB/TrEMBL
      K3W4L7
      Related
      ENSMUSP00000020262.5, ENSMUST00000020262.5
      Conserved Domains (1) summary
      cl29427
      Location:9284
      PhzC-PhzF; Phenazine biosynthesis-like protein

    RNA

    1. NR_175965.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC113107
    2. NR_175966.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC113107
    3. NR_175967.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC113107

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      62858319..62894592
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513983.2XP_006514046.1  phenazine biosynthesis-like domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      K3W4L7
      Conserved Domains (1) summary
      cl29427
      Location:46321
      PhzC-PhzF; Phenazine biosynthesis-like protein