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    Fcf1 FCF1 rRNA processing protein [ Mus musculus (house mouse) ]

    Gene ID: 73736, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fcf1provided by MGI
    Official Full Name
    FCF1 rRNA processing proteinprovided by MGI
    Primary source
    MGI:MGI:1920986
    See related
    Ensembl:ENSMUSG00000021243 AllianceGenome:MGI:1920986
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110008B24Rik
    Summary
    Acts upstream of or within endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human FCF1 (FCF1 rRNA-processing protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 46.5), liver E14 (RPKM 41.3) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Fcf1 in Genome Data Viewer
    Location:
    12 D1; 12 39.48 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (85017704..85030077)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (84970930..84983303)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene latent transforming growth factor beta binding protein 2 Neighboring gene RIKEN cDNA D030025P21 gene Neighboring gene apoptosis resistant E3 ubiquitin protein ligase 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:86311736-86311923 Neighboring gene STARR-positive B cell enhancer ABC_E1446 Neighboring gene STARR-seq mESC enhancer starr_32760 Neighboring gene STARR-seq mESC enhancer starr_32761 Neighboring gene YLP motif containing 1 Neighboring gene STARR-seq mESC enhancer starr_32762 Neighboring gene prospero homeobox 2 opposite strand Neighboring gene prospero homeobox 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    rRNA-processing protein FCF1 homolog
    Names
    FCF1 small subunit

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028632.2NP_082908.2  rRNA-processing protein FCF1 homolog

      See identical proteins and their annotated locations for NP_082908.2

      Status: VALIDATED

      Source sequence(s)
      BC094619, CJ085020
      Consensus CDS
      CCDS49113.1
      UniProtKB/Swiss-Prot
      Q505C6, Q8K261, Q9CTH6
      UniProtKB/TrEMBL
      E9Q186
      Related
      ENSMUSP00000021669.9, ENSMUST00000021669.15
      Conserved Domains (1) summary
      cd09864
      Location:55189
      PIN_Fcf1; PIN domain of rRNA-processing protein, Fcf1 (Utp24, YDR339C), and other eukaryotic homologs

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      85017704..85030077
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)