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    lpxB lipid-A-disaccharide synthase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 880521, updated on 11-Sep-2024

    Summary

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    Gene symbol
    lpxB
    Gene description
    lipid-A-disaccharide synthase
    Locus tag
    PA3643
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4081045..4082181, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene amino acid permease Neighboring gene ribonuclease HII Neighboring gene acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase Neighboring gene 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ Neighboring gene UDP-3-O-acylglucosamine N-acyltransferase Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning of the genes for lipid A disaccharide synthase and UDP-N-acetylglucosamine acyltransferase in Escherichia coli. Crowell DN, et al. J Bacteriol, 1986 Oct. PMID 3531165, Free PMC Article
    2. The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Cantarel BL, et al. Nucleic Acids Res, 2009 Jan. PMID 18838391, Free PMC Article
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipopolysaccharide biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lipid-A-disaccharide synthase
    NP_252333.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4081045..4082181 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252333.1 lipid-A-disaccharide synthase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252333.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A367MA85
      Conserved Domains (1) summary
      PRK00025
      Location:5 → 378
      lpxB; lipid-A-disaccharide synthase; Reviewed
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HXY8.1

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