Ptrhd1 peptidyl-tRNA hydrolase domain containing 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ptrhd1provided by MGI
Official Full Name: peptidyl-tRNA hydrolase domain containing 1provided by MGI
Primary source: MGI:MGI:1916959
See related: Ensembl:ENSMUSG00000096199 AllianceGenome:MGI:1916959
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2410017P09Rik
Summary: Predicted to enable aminoacyl-tRNA hydrolase activity. Orthologous to human PTRHD1 (peptidyl-tRNA hydrolase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in kidney adult (RPKM 12.6), adrenal adult (RPKM 5.7) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 12 A1.1; 12 2.04 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (4284013..4290123)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (4234013..4240123)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables aminoacyl-tRNA hydrolase activity	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

General protein information

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Preferred Names: putative peptidyl-tRNA hydrolase PTRHD1

Names: peptidyl-tRNA hydrolase domain-containing protein 1

NP_001191841.1

EC 3.1.1.29

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001204912.2 → NP_001191841.1 putative peptidyl-tRNA hydrolase PTRHD1

See identical proteins and their annotated locations for NP_001191841.1

Status: VALIDATED

Source sequence(s)

AC162932

Consensus CDS

CCDS56829.1

UniProtKB/Swiss-Prot

D3Z4S3

Related

ENSMUSP00000137070.2, ENSMUST00000179139.3

Conserved Domains (1) summary

cl19212
Location:25 → 139

PTH2_family; Peptidyl-tRNA hydrolase, type 2 (PTH2)_like . Peptidyl-tRNA hydrolase activity releases tRNA from the premature translation termination product peptidyl-tRNA. Two structurally different enzymes have been reported to encode such activity, Pth present in ...