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    oxyS [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 2847701, updated on 3-Dec-2024

    Summary

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    Official Symbol
    oxyS
    Primary source
    ECOCYC:EG31116
    Locus tag
    b4458
    See related
    ASAP:ABE-0047276
    Gene type
    ncRNA
    RNA name
    other
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3952
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    Genomic context

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    Sequence:
    NC_000913.3 (4158278..4158394, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene acetylglutamate kinase Neighboring gene argininosuccinate lyase Neighboring gene DNA-binding transcriptional dual regulator OxyR Neighboring gene soluble pyridine nucleotide transhydrogenase Neighboring gene DNA-binding transcriptional repressor FabR Neighboring gene DUF1422 domain-containing inner membrane protein YijD

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OxyS small RNA induces cell cycle arrest to allow DNA damage repair. Barshishat S, et al. EMBO J, 2018 Feb 1. PMID 29237698, Free PMC Article
    2. Effects of peroxides on susceptibilities of Escherichia coli and Mycobacterium smegmatis to isoniazid. Rosner JL, et al. Antimicrob Agents Chemother, 1994 Aug. PMID 7986015, Free PMC Article
    3. The novel oxyS RNA regulates expression of the sigma s subunit of Escherichia coli RNA polymerase. Zhang A, et al. Nucleic Acids Symp Ser, 1997. PMID 9478196
    4. Role for the oxyS gene in regulation of intracellular hydrogen peroxide in Escherichia coli. González-Flecha B, et al. J Bacteriol, 1999 Jun. PMID 10368161, Free PMC Article
    5. LNA-modified primers drastically improve hybridization to target RNA and reverse transcription. Fratczak A, et al. Biochemistry, 2009 Jan 27. PMID 19119855

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Escherichia coli OxyS RNA triggers cephalothin resistance by modulating the expression of CRP-associated genes.
      Title: Escherichia coli OxyS RNA triggers cephalothin resistance by modulating the expression of CRP-associated genes.
    2. OxyS induces a molecular checkpoint relay, leading to temporary cell cycle arrest to allow DNA damage repair
      Title: OxyS small RNA induces cell cycle arrest to allow DNA damage repair.
    3. The study verified that the A-rich linker region of OxyS sRNA binds Hfq at its distal side.
      Title: Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq.
    4. OxyS represses rpoS mRNA translation by sequestering Hfq rather than binding to rpoS mRNA
      Title: The influence of Escherichia coli Hfq mutations on RNA binding and sRNA•mRNA duplex formation in rpoS riboregulation.
    5. Hfq binding site in the fhlA mRNA leader region facilitates the OxyS-fhlA interaction.
      Title: An upstream Hfq binding site in the fhlA mRNA leader region facilitates the OxyS-fhlA interaction.
    Submit: New GeneRIF Correction

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