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    ldrB small toxic polypeptide LdrB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 2847735, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ldrB
    Official Full Name
    small toxic polypeptide LdrB
    Primary source
    ECOCYC:G0-9605
    Locus tag
    b4421
    See related
    ASAP:ABE-0047281
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1206
    Summary
    ldrB is one of a set of four Long Direct Repeats (LDRs), one of which has been shown to code for the toxin portion of a toxin-antitoxin pair. ldrA, ldrB and ldrC are clustered together as tandem repeats, with ldrD elsewhere on the genome. [More information is available at EcoCyc: G0-9605].
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    Genomic context

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    Sequence:
    NC_000913.3 (1269703..1269810, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene small toxic polypeptide LdrA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene small toxic polypeptide LdrC

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distribution of repetitive sequences on the leading and lagging strands of the Escherichia coli genome: comparative study of Long Direct Repeat (LDR) sequences. Kawano M, et al. DNA Res, 2002 Feb 28. PMID 11939563
    2. Hydrophobic peptides: novel regulators within bacterial membrane. Alix E, et al. Mol Microbiol, 2009 Apr. PMID 19210615
    3. Molecular characterization of long direct repeat (LDR) sequences expressing a stable mRNA encoding for a 35-amino-acid cell-killing peptide and a cis-encoded small antisense RNA in Escherichia coli. Kawano M, et al. Mol Microbiol, 2002 Jul. PMID 12123448
    4. Membranome: a database for proteome-wide analysis of single-pass membrane proteins. Lomize AL, et al. Nucleic Acids Res, 2017 Jan 4. PMID 27510400, Free PMC Article
    5. RNA antitoxins. Gerdes K, et al. Curr Opin Microbiol, 2007 Apr. PMID 17376733

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by EcoCyc

    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small toxic polypeptide LdrB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1269703..1269810 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_025298.1 small toxic polypeptide LdrB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_025298.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6D0UYG9
      Conserved Domains (1) summary
      pfam13940
      Location:1 → 35
      Ldr_toxin; Toxin Ldr, type I toxin-antitoxin system
    Nucleotide Protein
    Heading Accession and Version

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