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    rtcA RNA 3'-terminal phosphate cyclase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 2847707, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rtcA
    Official Full Name
    RNA 3'-terminal phosphate cyclase
    Primary source
    ECOCYC:G7750
    Locus tag
    b4475
    See related
    ASAP:ABE-0174104
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    b3419; b3420; ECK3406; yhgJ; yhgK
    Summary
    RNA 3'-terminal phosphate cyclase converts the 3'-terminal phosphate of various RNA substrates into the 2',3'-cyclic phosphodiester in an ATP-dependent reaction. [More information is available at EcoCyc: G7750].
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    Genomic context

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    Sequence:
    NC_000913.3 (3555833..3556849, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene maltodextrin phosphorylase Neighboring gene DNA-binding transcriptional activator MalT Neighboring gene RNA-splicing ligase Neighboring gene DNA-binding transcriptional activator RtcR Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the adenylation site in the RNA 3'-terminal phosphate cyclase from Escherichia coli. Billy E, et al. J Biol Chem, 1999 Dec 3. PMID 10574971
    2. Cyclases of the 3'-terminal phosphate in RNA: a new family of RNA processing enzymes conserved in eucarya, bacteria and archaea. Filipowicz W, et al. Acta Biochim Pol, 1998. PMID 10397337
    3. The nucleotide sequence of the malT gene encoding the positive regulator of the Escherichia coli maltose regulon. Cole ST, et al. Gene, 1986. PMID 3015733
    4. The human RNA 3'-terminal phosphate cyclase is a member of a new family of proteins conserved in Eucarya, Bacteria and Archaea. Genschik P, et al. EMBO J, 1997 May 15. PMID 9184239, Free PMC Article
    5. Crystal structure of RNA 3'-terminal phosphate cyclase, a ubiquitous enzyme with unusual topology. Palm GJ, et al. Structure, 2000 Jan 15. PMID 10673421

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA-3'-phosphate cyclase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA-3'-phosphate cyclase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA-3'-phosphate cyclase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RNA 3'-terminal phosphate cyclase
    YP_026219.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3555833..3556849 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026219.1 RNA 3'-terminal phosphate cyclase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026219.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1X3IVR0, A0A1X3JBY9
      Conserved Domains (1) summary
      PRK04204
      Location:3 → 335
      PRK04204; RNA 3'-terminal phosphate cyclase
    Nucleotide Protein
    Heading Accession and Version

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