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    dgoD D-galactonate dehydratase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 2847765, updated on 17-Dec-2024

    Summary

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    Official Symbol
    dgoD
    Official Full Name
    D-galactonate dehydratase
    Primary source
    ECOCYC:GB4478
    Locus tag
    b4478
    See related
    ASAP:ABE-0174106
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    b3692; ECK3684; yidU
    Summary
    A genome sequence error, now repaired, previously fused dgoA and dgoD. [More information is available at EcoGene: EG20050]. D-galactonate dehydratase catalyzes the first step in the degradation of D-galactonate, the dehydration of D-galactonate to form 2-dehydro-3-deoxygalactonate . [More information is available at EcoCyc: GB4478].
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    Genomic context

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    Sequence:
    NC_000913.3 (3871850..3872998, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF3748 domain-containing galacturonate catabolism protein YidR Neighboring gene colicin M resistance protein Neighboring gene D-galactonate:H(+) symporter Neighboring gene 2-dehydro-3-deoxy-6-phosphogalactonate aldolase Neighboring gene 2-dehydro-3-deoxygalactonokinase Neighboring gene DNA-binding transcriptional regulator DgoR Neighboring gene putative lipoprotein YidX

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids. Babbitt PC, et al. Science, 1995 Feb 24. PMID 7855594
    2. The utilisation of D-galactonate and D-2-oxo-3-deoxygalactonate by Escherichia coli K-12. Biochemical and genetical studies. Cooper RA. Arch Microbiol, 1978 Aug 1. PMID 211976
    3. D-Galactonate utilisation by enteric bacteria. The catabolic pathway in Escherichia coli. Deacon J, et al. FEBS Lett, 1977 May 15. PMID 324806
    4. Molecular and Functional Insights into the Regulation of d-Galactonate Metabolism by the Transcriptional Regulator DgoR in Escherichia coli. Singh B, et al. J Bacteriol, 2019 Feb 15. PMID 30455279, Free PMC Article
    5. DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication. Burland V, et al. Genomics, 1993 Jun. PMID 7686882

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on complete protein
      Title: A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables galactonate dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydro-lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-galactonate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in D-galactonate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within D-galactonate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in amino acid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    D-galactonate dehydratase
    YP_026237.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3871850..3872998 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026237.1 D-galactonate dehydratase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026237.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A418GGR6, A0A8S7XIN4
      Conserved Domains (1) summary
      PRK14017
      Location:1 → 382
      PRK14017; galactonate dehydratase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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