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    PQBP1 polyglutamine binding protein 1 [ Homo sapiens (human) ]

    Gene ID: 10084, updated on 10-Dec-2024

    Summary

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    Official Symbol
    PQBP1provided by HGNC
    Official Full Name
    polyglutamine binding protein 1provided by HGNC
    Primary source
    HGNC:HGNC:9330
    See related
    Ensembl:ENSG00000102103 MIM:300463; AllianceGenome:HGNC:9330
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SHS; MRX2; MRX55; MRXS3; MRXS8; NPW38; RENS1
    Summary
    This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked cognitive disability. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.[provided by RefSeq, Nov 2009]
    Expression
    Ubiquitous expression in ovary (RPKM 25.3), adrenal (RPKM 17.1) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See PQBP1 in Genome Data Viewer
    Location:
    Xp11.23
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (48897930..48903143)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (48308411..48313619)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (48755213..48760420)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:48689342-48689842 Neighboring gene ES cell expressed Ras Neighboring gene proprotein convertase subtilisin/kexin type 1 inhibitor Neighboring gene BRD4-independent group 4 enhancer GRCh37_chrX:48726714-48727913 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20824 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29614 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29615 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29616 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29617 Neighboring gene translocase of inner mitochondrial membrane 17B Neighboring gene solute carrier family 35 member A2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20825 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29618 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29619 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29620 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20826 Neighboring gene Pim-2 proto-oncogene, serine/threonine kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Whole gene duplication of the PQBP1 gene in syndrome resembling Renpenning. Flynn M, et al. Am J Med Genet A, 2011 Jan. PMID 21204222
    2. Mutations in the polyglutamine binding protein 1 gene cause X-linked mental retardation. Kalscheuer VM, et al. Nat Genet, 2003 Dec. PMID 14634649
    3. Fatal Attraction: The Case of Toxic Soluble Dimers of Truncated PQBP-1 Mutants in X-Linked Intellectual Disability. Chen YW, et al. Int J Mol Sci, 2021 Feb 24. PMID 33668121, Free PMC Article
    4. Novel truncating mutations in the polyglutamine tract binding protein 1 gene (PQBP1) cause Renpenning syndrome and X-linked mental retardation in another family with microcephaly. Lenski C, et al. Am J Hum Genet, 2004 Apr. PMID 15024694, Free PMC Article
    5. Genotype-phenotype studies in three families with mutations in the polyglutamine-binding protein 1 gene (PQBP1). Kleefstra T, et al. Clin Genet, 2004 Oct. PMID 15355434

    See all (118) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Splicing Factor PQBP1 Curtails BAX Expression to Promote Ovarian Cancer Progression.
      Title: Splicing Factor PQBP1 Curtails BAX Expression to Promote Ovarian Cancer Progression.
    2. The role of PQBP1 in neural development and function.
      Title: The role of PQBP1 in neural development and function.
    3. PQBP1: The Key to Intellectual Disability, Neurodegenerative Diseases, and Innate Immunity.
      Title: PQBP1: The Key to Intellectual Disability, Neurodegenerative Diseases, and Innate Immunity.
    4. Novel regulation of the eEF2K/eEF2 pathway: prospects of 'PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation'.
      Title: Novel regulation of the eEF2K/eEF2 pathway: prospects of 'PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation'.
    5. Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation.
      Title: Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation.
    6. Fatal Attraction: The Case of Toxic Soluble Dimers of Truncated PQBP-1 Mutants in X-Linked Intellectual Disability.
      Title: Fatal Attraction: The Case of Toxic Soluble Dimers of Truncated PQBP-1 Mutants in X-Linked Intellectual Disability.
    7. PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation.
      Title: PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation.
    8. Frequency and distribution of polyQ disease intermediate-length repeat alleles in healthy Italian population.
      Title: Frequency and distribution of polyQ disease intermediate-length repeat alleles in healthy Italian population.
    9. Renpenning syndrome in an Indian patient.
      Title: Renpenning syndrome in an Indian patient.
    10. Renpenning syndrome in a female.
      Title: Renpenning syndrome in a female.
    Submit: New GeneRIF Correction See all GeneRIFs (37)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Renpenning syndrome
    MedGen: C0796135 OMIM: 309500 GeneReviews: Not available
    		not available

    Copy number response

    Description
    Copy number response
    Triplosensitivity

    No evidence available (Last evaluated 2020-04-09)

    ClinGen Genome Curation Page
    Haploinsufficency

    Sufficient evidence for dosage pathogenicity (Last evaluated 2020-04-09)

    ClinGen Genome Curation PagePubMed

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ribonucleoprotein complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ribonucleoprotein complex binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transcription coactivator activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of innate immune response IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in alternative mRNA splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cellular response to exogenous dsRNA IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in defense response to virus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in neuron projection development ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of defense response to virus by host IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of type I interferon production IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of RNA splicing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of dendrite morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasmic stress granule IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in neuronal ribonucleoprotein granule IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nuclear body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nuclear speck ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    located_in nucleus TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    polyglutamine-binding protein 1
    Names
    38 kDa nuclear protein containing a WW domain
    polyglutamine tract-binding protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_015967.2 RefSeqGene

      Range
      5002..10215
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001032381.2 → NP_001027553.1  polyglutamine-binding protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001027553.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, and 5 all encode the same protein (isoform 1).
      Source sequence(s)
      BC012358, CN292761
      Consensus CDS
      CCDS14309.1
      UniProtKB/Swiss-Prot
      C9JQA1, O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4
      UniProtKB/TrEMBL
      A0A0S2Z4V5, A0A0S2Z556
      Related
      ENSP00000365747.1, ENST00000376563.6
      Conserved Domains (1) summary
      smart00456
      Location:47 → 78
      WW; Domain with 2 conserved Trp (W) residues

    2. NM_001032382.2 → NP_001027554.1  polyglutamine-binding protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001027554.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, and 5 all encode the same protein (isoform 1).
      Source sequence(s)
      AB016533, BC012358, CN292761
      Consensus CDS
      CCDS14309.1
      UniProtKB/Swiss-Prot
      C9JQA1, O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4
      UniProtKB/TrEMBL
      A0A0S2Z4V5, A0A0S2Z556
      Related
      ENSP00000391759.2, ENST00000447146.7
      Conserved Domains (1) summary
      smart00456
      Location:47 → 78
      WW; Domain with 2 conserved Trp (W) residues

    3. NM_001032383.2 → NP_001027555.1  polyglutamine-binding protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001027555.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, and 5 all encode the same protein (isoform 1).
      Source sequence(s)
      BC012358, BX362311, CN292761
      Consensus CDS
      CCDS14309.1
      UniProtKB/Swiss-Prot
      C9JQA1, O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4
      UniProtKB/TrEMBL
      A0A0S2Z4V5, A0A0S2Z556
      Related
      ENSP00000498362.1, ENST00000651767.1
      Conserved Domains (1) summary
      smart00456
      Location:47 → 78
      WW; Domain with 2 conserved Trp (W) residues

    4. NM_001032384.1 → NP_001027556.1  polyglutamine-binding protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001027556.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, and 5 all encode the same protein (isoform 1).
      Source sequence(s)
      AJ005893, BC012358, BE396796
      Consensus CDS
      CCDS14309.1
      UniProtKB/Swiss-Prot
      C9JQA1, O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4
      UniProtKB/TrEMBL
      A0A0S2Z4V5, A0A0S2Z556
      Related
      ENSP00000379985.1, ENST00000396763.6
      Conserved Domains (1) summary
      smart00456
      Location:47 → 78
      WW; Domain with 2 conserved Trp (W) residues

    5. NM_001167989.2 → NP_001161461.1  polyglutamine-binding protein 1 isoform 4

      See identical proteins and their annotated locations for NP_001161461.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR and uses a different splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 4) is shorter by 1 aa when it is compared to isoform 1.
      Source sequence(s)
      AJ973597, AJ973606, BE385548, BI818141, CD365745, CN292761
      UniProtKB/TrEMBL
      A0A0S2Z556
      Conserved Domains (1) summary
      smart00456
      Location:47 → 78
      WW; Domain with 2 conserved Trp (W) residues

    6. NM_001167990.2 → NP_001161462.1  polyglutamine-binding protein 1 isoform 5

      See identical proteins and their annotated locations for NP_001161462.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR and uses a different splice site in the coding region, compared to variant 1. The resulting protein (isoform 5) is shorter when it is compared to isoform 1.
      Source sequence(s)
      BC012358, CD051018
      UniProtKB/TrEMBL
      A0A0S2Z556

    7. NM_001167992.1 → NP_001161464.1  polyglutamine-binding protein 1 isoform 6

      See identical proteins and their annotated locations for NP_001161464.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) lacks a 5' UTR and uses different splice sites in the coding region, compared to variant 1. The resulting protein (isoform 6) is shorter when it is compared to isoform 1.
      Source sequence(s)
      AJ973605, BC012358, CN292761
      UniProtKB/Swiss-Prot
      O60828

    8. NM_005710.2 → NP_005701.1  polyglutamine-binding protein 1 isoform 1

      See identical proteins and their annotated locations for NP_005701.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1, 2, 3, 4, and 5 all encode the same protein (isoform 1).
      Source sequence(s)
      AJ005893, BC012358
      Consensus CDS
      CCDS14309.1
      UniProtKB/Swiss-Prot
      C9JQA1, O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4
      UniProtKB/TrEMBL
      A0A0S2Z4V5, A0A0S2Z556
      Related
      ENSP00000218224.4, ENST00000218224.9
      Conserved Domains (1) summary
      smart00456
      Location:47 → 78
      WW; Domain with 2 conserved Trp (W) residues

    9. NM_144495.3 → NP_652766.1  polyglutamine-binding protein 1 isoform 3

      See identical proteins and their annotated locations for NP_652766.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) contains a different 5' UTR and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1. Variant 7 is also known as variant PQBP-1d.
      Source sequence(s)
      AJ973593, BC012358, CN292761
      Consensus CDS
      CCDS55412.1
      UniProtKB/Swiss-Prot
      O60828
      Related
      ENSP00000365750.4, ENST00000376566.8
      Conserved Domains (1) summary
      smart00456
      Location:47 → 78
      WW; Domain with 2 conserved Trp (W) residues

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      48897930..48903143
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017029207.2 → XP_016884696.1  polyglutamine-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A0S2Z556
      Conserved Domains (1) summary
      smart00456
      Location:47 → 78
      WW; Domain with 2 conserved Trp (W) residues

    2. XM_047441754.1 → XP_047297710.1  polyglutamine-binding protein 1 isoform X3

    3. XM_005272571.4 → XP_005272628.1  polyglutamine-binding protein 1 isoform X2

      See identical proteins and their annotated locations for XP_005272628.1

      UniProtKB/TrEMBL
      A0A0S2Z556
      Conserved Domains (1) summary
      smart00456
      Location:47 → 78
      WW; Domain with 2 conserved Trp (W) residues

    4. XM_005272572.5 → XP_005272629.1  polyglutamine-binding protein 1 isoform X3

      See identical proteins and their annotated locations for XP_005272629.1

      UniProtKB/Swiss-Prot
      O60828
      Related
      ENSP00000247140.4, ENST00000247140.8
      Conserved Domains (1) summary
      smart00456
      Location:47 → 78
      WW; Domain with 2 conserved Trp (W) residues

    5. XM_047441753.1 → XP_047297709.1  polyglutamine-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A0S2Z556

    6. XM_011543884.3 → XP_011542186.1  polyglutamine-binding protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011542186.1

      UniProtKB/Swiss-Prot
      C9JQA1, O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4
      UniProtKB/TrEMBL
      A0A0S2Z4V5, A0A0S2Z556
      Conserved Domains (1) summary
      smart00456
      Location:47 → 78
      WW; Domain with 2 conserved Trp (W) residues

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_025791820.1 Reference GRCh38.p14 PATCHES

      Range
      56765..61978
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054333395.1 → XP_054189370.1  polyglutamine-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A0S2Z556

    2. XM_054333397.1 → XP_054189372.1  polyglutamine-binding protein 1 isoform X3

    3. XM_054333394.1 → XP_054189369.1  polyglutamine-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A0S2Z556

    4. XM_054333398.1 → XP_054189373.1  polyglutamine-binding protein 1 isoform X3

    5. XM_054333396.1 → XP_054189371.1  polyglutamine-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A0S2Z556

    6. XM_054333393.1 → XP_054189368.1  polyglutamine-binding protein 1 isoform X1

      UniProtKB/Swiss-Prot
      C9JQA1, O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4
      UniProtKB/TrEMBL
      A0A0S2Z4V5, A0A0S2Z556

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      48308411..48313619
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054326332.1 → XP_054182307.1  polyglutamine-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A0S2Z556

    2. XM_054326334.1 → XP_054182309.1  polyglutamine-binding protein 1 isoform X3

    3. XM_054326331.1 → XP_054182306.1  polyglutamine-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A0S2Z556

    4. XM_054326335.1 → XP_054182310.1  polyglutamine-binding protein 1 isoform X3

    5. XM_054326333.1 → XP_054182308.1  polyglutamine-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A0S2Z556

    6. XM_054326330.1 → XP_054182305.1  polyglutamine-binding protein 1 isoform X1

      UniProtKB/Swiss-Prot
      C9JQA1, O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4
      UniProtKB/TrEMBL
      A0A0S2Z4V5, A0A0S2Z556

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001032385.1: Suppressed sequence

      Description
      NM_001032385.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.

    2. NM_144494.1: Suppressed sequence

      Description
      NM_144494.1: This RefSeq was permanently suppressed because it contains intronic sequence and insufficient support exists for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O60828.1 GenPept UniProtKB/Swiss-Prot:O60828

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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