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    bfrB bacterioferritin [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 879026, updated on 24-Aug-2024

    Summary

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    Gene symbol
    bfrB
    Gene description
    bacterioferritin
    Locus tag
    PA3531
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3950284..3950760)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene peroxidase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Concerted motions networking pores and distant ferroxidase centers enable bacterioferritin function and iron traffic. Yao H, et al. Biochemistry, 2015 Mar 3. PMID 25640193, Free PMC Article
    2. Two distinct ferritin-like molecules in Pseudomonas aeruginosa: the product of the bfrA gene is a bacterial ferritin (FtnA) and not a bacterioferritin (Bfr). Yao H, et al. Biochemistry, 2011 Jun 14. PMID 21574546, Free PMC Article
    3. Characterization of the Bacterioferritin/Bacterioferritin Associated Ferredoxin Protein-Protein Interaction in Solution and Determination of Binding Energy Hot Spots. Wang Y, et al. Biochemistry, 2015 Oct 13. PMID 26368531, Free PMC Article
    4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The study reports the strength of the P. aeruginosa BfrB:Bfd association using surface plasmon resonance and isothermal titration calorimetry as well as determines the binding energy hot spots at the protein-protein interaction interface. [Bfd]
      Title: Characterization of the Bacterioferritin/Bacterioferritin Associated Ferredoxin Protein-Protein Interaction in Solution and Determination of Binding Energy Hot Spots.
    2. structures show a large number of previously unknown iron binding sites in the interior cavity and B-pores of BfrB, which reveal in unprecedented detail conduits followed by iron and phosphate ions across the BfrB shell
      Title: Concerted motions networking pores and distant ferroxidase centers enable bacterioferritin function and iron traffic.
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    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular sequestering of iron ion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bacterioferritin
    NP_252221.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3950284..3950760
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252221.1 bacterioferritin [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252221.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9HY79
      Conserved Domains (1) summary
      COG2193
      Location:1 → 157
      Bfr; Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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