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    RPL23A ribosomal 60S subunit protein L23A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852191, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPL23A
    Official Full Name
    ribosomal 60S subunit protein L23A
    Primary source
    SGD:S000000183
    Locus tag
    YBL087C
    See related
    AllianceGenome:SGD:S000000183; FungiDB:YBL087C; VEuPathDB:YBL087C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable large ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL23 (ribosomal protein L23). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPL23A in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_001134.8 (59822..60739, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene amino acid transporter Neighboring gene DNA-binding protein kinase TEL1 Neighboring gene uncharacterized protein Neighboring gene Boi1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The crystal structure of protein-transporting chaperone BCP1 from Saccharomyces cerevisiae. Lin MH, et al. J Struct Biol, 2020 Oct 1. PMID 32805410
    2. Yeast ribosomal/cytochrome c SET domain methyltransferase subfamily: identification of Rpl23ab methylation sites and recognition motifs. Porras-Yakushi TR, et al. J Biol Chem, 2007 Apr 27. PMID 17327221
    3. A novel SET domain methyltransferase modifies ribosomal protein Rpl23ab in yeast. Porras-Yakushi TR, et al. J Biol Chem, 2005 Oct 14. PMID 16096273
    4. Dual protection by Bcp1 and Rkm1 ensures incorporation of uL14 into pre-60S ribosomal subunits. Yeh MC, et al. J Cell Biol, 2024 Aug 5. PMID 39007857, Free PMC Article
    5. YKE4 (YIL023C) encodes a bidirectional zinc transporter in the endoplasmic reticulum of Saccharomyces cerevisiae. Kumánovics A, et al. J Biol Chem, 2006 Aug 11. PMID 16760462

    See all (123) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables large ribosomal subunit rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L23A
    NP_009466.1
    • Ribosomal 60S subunit protein L23A; homologous to mammalian ribosomal protein L23 and bacterial L14; RPL23A has a paralog, RPL23B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      59822..60739 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178327.1 → NP_009466.1  TPA: ribosomal 60S subunit protein L23A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009466.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DM23, P04451, P0CX41, P0CX42
      UniProtKB/TrEMBL
      A6ZKL6, B3LNL8, C8Z3V8, G2W8S6, N1P744
      Conserved Domains (1) summary
      PTZ00054
      Location:5 → 137
      PTZ00054; 60S ribosomal protein L23; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CX41.1
    P0CX42.1

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