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    Susd6 sushi domain containing 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 678893, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Susd6provided by RGD
    Official Full Name
    sushi domain containing 6provided by RGD
    Primary source
    RGD:1595528
    See related
    EnsemblRapid:ENSRNOG00000045941 AllianceGenome:RGD:1595528
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in DNA damage response. Orthologous to human SUSD6 (sushi domain containing 6). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Lung (RPKM 89.0), Spleen (RPKM 78.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Susd6 in Genome Data Viewer
    Location:
    6q24
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (106130183..106262900)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (100437834..100531621)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (104437104..104532522)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479447 Neighboring gene solute carrier family 39, member 9 Neighboring gene pleckstrin homology and coiled-coil domain containing D1 Neighboring gene coiled-coil domain containing 177 Neighboring gene serine and arginine rich splicing factor 5 Neighboring gene solute carrier family 10 member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. DRAGO (KIAA0247), a new DNA damage-responsive, p53-inducible gene that cooperates with p53 as oncosuppressor. [Corrected]. Polato F, et al. J Natl Cancer Inst, 2014 Apr. PMID 24652652, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in DNA damage response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA damage response ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    sushi domain-containing protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398930.2 → NP_001385859.1  sushi domain-containing protein 6 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A096MK85, A6JDK3
      Related
      ENSRNOP00000068418.1, ENSRNOT00000076485.4
      Conserved Domains (1) summary
      cd00033
      Location:42 → 98
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

    2. NM_001428965.1 → NP_001415894.1  sushi domain-containing protein 6 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A6JDK2, M0R5N9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      106130183..106262900
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063262461.1 → XP_063118531.1  sushi domain-containing protein 6 isoform X1

      UniProtKB/TrEMBL
      A6JDK2, M0R5N9

    2. XM_063262462.1 → XP_063118532.1  sushi domain-containing protein 6 isoform X1

      UniProtKB/TrEMBL
      A6JDK2, M0R5N9

    3. XM_039113294.2 → XP_038969222.1  sushi domain-containing protein 6 isoform X1

      UniProtKB/TrEMBL
      A6JDK2, M0R5N9
      Conserved Domains (1) summary
      cd00033
      Location:63 → 119
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

    4. XM_039113295.2 → XP_038969223.1  sushi domain-containing protein 6 isoform X1

      UniProtKB/TrEMBL
      A6JDK2, M0R5N9
      Conserved Domains (1) summary
      cd00033
      Location:63 → 119
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

    5. XM_039113292.2 → XP_038969220.1  sushi domain-containing protein 6 isoform X1

      UniProtKB/TrEMBL
      A6JDK2, M0R5N9
      Conserved Domains (1) summary
      cd00033
      Location:63 → 119
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

    6. XM_063262465.1 → XP_063118535.1  sushi domain-containing protein 6 isoform X2

      UniProtKB/TrEMBL
      A0A096MK85, A6JDK3

    7. XM_039113293.2 → XP_038969221.1  sushi domain-containing protein 6 isoform X1

      UniProtKB/TrEMBL
      A6JDK2, M0R5N9
      Conserved Domains (1) summary
      cd00033
      Location:63 → 119
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

    8. XM_063262463.1 → XP_063118533.1  sushi domain-containing protein 6 isoform X2

      UniProtKB/TrEMBL
      A0A096MK85, A6JDK3

    9. XM_039113291.2 → XP_038969219.1  sushi domain-containing protein 6 isoform X1

      Related
      ENSRNOP00000064712.2, ENSRNOT00000070995.5
      Conserved Domains (1) summary
      cd00033
      Location:63 → 119
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

    10. XM_039113296.2 → XP_038969224.1  sushi domain-containing protein 6 isoform X1

      UniProtKB/TrEMBL
      A6JDK2, M0R5N9
      Conserved Domains (1) summary
      cd00033
      Location:63 → 119
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

    11. XM_039113297.2 → XP_038969225.1  sushi domain-containing protein 6 isoform X1

      UniProtKB/TrEMBL
      A6JDK2, M0R5N9
      Conserved Domains (1) summary
      cd00033
      Location:63 → 119
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

    12. XM_063262464.1 → XP_063118534.1  sushi domain-containing protein 6 isoform X2

      UniProtKB/TrEMBL
      A0A096MK85, A6JDK3
    Nucleotide Protein Strain
    Heading Accession and Version

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