U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Rab39a RAB39A, member RAS oncogene family [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315668, updated on 27-Nov-2024

    Summary

    Official Symbol
    Rab39aprovided by RGD
    Official Full Name
    RAB39A, member RAS oncogene familyprovided by RGD
    Primary source
    RGD:1311286
    See related
    EnsemblRapid:ENSRNOG00000063146 AllianceGenome:RGD:1311286
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Rab39
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in phagosome acidification and phagosome-lysosome fusion. Predicted to be located in phagocytic vesicle. Orthologous to human RAB39A (RAB39A, member RAS oncogene family). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 84.0), Spleen (RPKM 33.5) and 5 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rab39a in Genome Data Viewer
    Location:
    8q24
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (62984434..63002053, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (54088246..54105867, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (58275984..58292995, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094160 Neighboring gene cullin 5 Neighboring gene small nucleolar RNA SNORA61 Neighboring gene uncharacterized LOC134480167 Neighboring gene solute carrier family 35, member F2 Neighboring gene sarcolipin

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in Rab protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in phagosome acidification ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phagosome-lysosome fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phagosome-lysosome fusion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in phagocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in synaptic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ras-related protein Rab-39A
    Names
    RAB39, member RAS oncogene family

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108148.3NP_001101618.1  ras-related protein Rab-39A

      See identical proteins and their annotated locations for NP_001101618.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6J4J9, D3ZZP2
      Related
      ENSRNOP00000095397.1, ENSRNOT00000118207.2
      Conserved Domains (1) summary
      cd04111
      Location:7217
      Rab39; Rab GTPase family 39 (Rab39)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      62984434..63002053 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)