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    Abhd3 abhydrolase domain containing 3, phospholipase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291793, updated on 27-Nov-2024

    Summary

    Official Symbol
    Abhd3provided by RGD
    Official Full Name
    abhydrolase domain containing 3, phospholipaseprovided by RGD
    Primary source
    RGD:1310655
    See related
    EnsemblRapid:ENSRNOG00000029370 AllianceGenome:RGD:1310655
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable carboxylic ester hydrolase activity. Predicted to be involved in medium-chain fatty acid biosynthetic process; medium-chain fatty acid catabolic process; and phosphatidylcholine metabolic process. Predicted to be located in membrane. Orthologous to human ABHD3 (abhydrolase domain containing 3, phospholipase). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Adrenal (RPKM 938.0), Brain (RPKM 314.5) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Abhd3 in Genome Data Viewer
    Location:
    18p13
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (1996010..2051311, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (1723203..1778488, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (1892413..1946840, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134482900 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene small nuclear ribonucleoprotein D1 polypeptide Neighboring gene histidine-rich glycoprotein-like Neighboring gene MIB E3 ubiquitin protein ligase 1 Neighboring gene small nucleolar RNA SNORA70 Neighboring gene microRNA 133a-1 Neighboring gene microRNA 3582

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables acetylesterase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables monoacylglycerol lipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phospholipase A1 activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phospholipase A1 activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables phospholipase A2 activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phospholipase A2 activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in medium-chain fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in medium-chain fatty acid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phosphatidylcholine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phosphatidylcholine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    phospholipase ABHD3
    Names
    abhydrolase domain-containing protein 3
    NP_001099632.1
    XP_063133339.1
    XP_063133340.1
    XP_063133341.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106162.1NP_001099632.1  phospholipase ABHD3

      See identical proteins and their annotated locations for NP_001099632.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474073
      UniProtKB/TrEMBL
      A0A8I5ZSG0, A6KNE8
      Related
      ENSRNOP00000081406.1, ENSRNOT00000110127.2
      Conserved Domains (2) summary
      PLN02511
      Location:39403
      PLN02511; hydrolase
      cl21494
      Location:92398
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      1996010..2051311 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277271.1XP_063133341.1  phospholipase ABHD3 isoform X3

    2. XM_063277270.1XP_063133340.1  phospholipase ABHD3 isoform X2

    3. XM_063277269.1XP_063133339.1  phospholipase ABHD3 isoform X1