Slc6a20b solute carrier family 6 member 20b [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc6a20bprovided by RGD
Official Full Name: solute carrier family 6 member 20bprovided by RGD
Primary source: RGD:1566368
See related: EnsemblRapid:ENSRNOG00000006010 AllianceGenome:RGD:1566368
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1566368
Summary: Enables L-proline transmembrane transporter activity; amino-acid betaine transmembrane transporter activity; and proline:sodium symporter activity. Involved in L-proline import across plasma membrane and amino-acid betaine transport. Predicted to be located in apical plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 152.8), Brain (RPKM 19.6) and 1 other tissue See more
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (132108481..132158422, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (123234731..123278306, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (132663281..132709485, complement)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables L-proline transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables amino acid transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables amino-acid betaine transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables proline:sodium symporter activity	IDA Inferred from Direct Assay more info	PubMed
enables proline:sodium symporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables solute:sodium symporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables symporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in L-proline import across plasma membrane	IDA Inferred from Direct Assay more info	PubMed
involved_in amino acid import across plasma membrane	IDA Inferred from Direct Assay more info	PubMed
involved_in amino acid transport	IDA Inferred from Direct Assay more info	PubMed
involved_in amino-acid betaine transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in glycine import across plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in apical plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_063266353.1 → XP_063122423.1 sodium- and chloride-dependent transporter XTRP3B isoform X2

UniProtKB/TrEMBL

F1LZT7
XM_002729986.7 → XP_002730032.2 sodium- and chloride-dependent transporter XTRP3B isoform X1

See identical proteins and their annotated locations for XP_002730032.2

UniProtKB/Swiss-Prot

Q64093

UniProtKB/TrEMBL

A0A8I6AX01

Related

ENSRNOP00000008172.8, ENSRNOT00000008172.9

Conserved Domains (1) summary

cl00456
Location:43 → 618

SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain