Ildr1 immunoglobulin-like domain containing receptor 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ildr1provided by RGD
Official Full Name: immunoglobulin-like domain containing receptor 1provided by RGD
Primary source: RGD:1307792
See related: EnsemblRapid:ENSRNOG00000002289 AllianceGenome:RGD:1307792
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1307792
Summary: Predicted to enable high-density lipoprotein particle receptor activity and identical protein binding activity. Predicted to be involved in several processes, including epithelial structure maintenance; protein localization to tricellular tight junction; and tricellular tight junction assembly. Predicted to act upstream of or within cellular response to leukemia inhibitory factor and positive regulation of peptide hormone secretion. Predicted to be located in cytosol and tricellular tight junction. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 42. Orthologous to human ILDR1 (immunoglobulin like domain containing receptor 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Kidney (RPKM 93.0), Lung (RPKM 20.3) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 11q22

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	11	NC_086029.1 (77591146..77624268, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	11	NC_051346.1 (64085774..64118760, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	11	NC_005110.4 (67004042..67037115, complement)

Chromosome 11 - NC_086029.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables high-density lipoprotein particle receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables high-density lipoprotein particle receptor activity	ISO Inferred from Sequence Orthology more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellular response to leukemia inhibitory factor	ISO Inferred from Sequence Orthology more info
involved_in epithelial structure maintenance	ISO Inferred from Sequence Orthology more info
acts_upstream_of establishment of localization in cell	ISO Inferred from Sequence Orthology more info
acts_upstream_of peptide hormone secretion	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of peptide hormone secretion	ISO Inferred from Sequence Orthology more info
involved_in protein localization to tricellular tight junction	ISO Inferred from Sequence Orthology more info
involved_in regulation of RNA splicing	ISO Inferred from Sequence Orthology more info
involved_in response to fatty acid	ISO Inferred from Sequence Orthology more info
involved_in tricellular tight junction assembly	ISO Inferred from Sequence Orthology more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in bicellular tight junction	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in endomembrane system	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info
located_in tight junction	ISO Inferred from Sequence Orthology more info
located_in tricellular tight junction	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: immunoglobulin-like domain-containing receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.