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    PRM8 pheromone-regulated DUP240 family protein PRM8 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852828, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PRM8
    Official Full Name
    pheromone-regulated DUP240 family protein PRM8
    Primary source
    SGD:S000003021
    Locus tag
    YGL053W
    See related
    AllianceGenome:SGD:S000003021; FungiDB:YGL053W; VEuPathDB:YGL053W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in vesicle-mediated transport. Located in endoplasmic reticulum and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PRM8 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (402589..403302)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene cornichon family protein Neighboring gene tRNA-Glu Neighboring gene DUP240 family protein MST27 Neighboring gene tRNA-Arg

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The characterization of two new clusters of duplicated genes suggests a 'Lego' organization of the yeast Saccharomyces cerevisiae chromosomes. Feuermann M, et al. Yeast, 1997 Jul. PMID 9234674
    2. Expansion and contraction of the DUP240 multigene family in Saccharomyces cerevisiae populations. Leh-Louis V, et al. Genetics, 2004 Aug. PMID 15342502, Free PMC Article
    3. Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae. Sandmann T, et al. Mol Biol Cell, 2003 Aug. PMID 12925749, Free PMC Article
    4. Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Miller EA, et al. Cell, 2003 Aug 22. PMID 12941277
    5. Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating. Heiman MG, et al. J Cell Biol, 2000 Oct 30. PMID 11062271, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pheromone-regulated DUP240 family protein PRM8
    NP_011462.1
    • Pheromone-regulated protein; contains with 2 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; forms a complex with Prp9p in the ER; member of DUP240 gene family; PRM8 has a paralog, PRM9, that arose from a segmental duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      402589..403302
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180918.1 → NP_011462.1  TPA: pheromone-regulated DUP240 family protein PRM8 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011462.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VU88, P53174
      UniProtKB/TrEMBL
      Q687B0
      Conserved Domains (1) summary
      pfam00674
      Location:80 → 171
      DUP; DUP family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53174.1

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