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    Slc22a7 solute carrier family 22 member 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 89776, updated on 27-Nov-2024

    Summary

    Official Symbol
    Slc22a7provided by RGD
    Official Full Name
    solute carrier family 22 member 7provided by RGD
    Primary source
    RGD:621699
    See related
    EnsemblRapid:ENSRNOG00000018420 AllianceGenome:RGD:621699
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Oat2; Livtr; rOAT2
    Summary
    Enables prostaglandin transmembrane transporter activity and sodium-independent organic anion transmembrane transporter activity. Involved in prostaglandin transport. Located in apical plasma membrane and basolateral plasma membrane. Orthologous to human SLC22A7 (solute carrier family 22 member 7). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Liver (RPKM 159.8) and Kidney (RPKM 85.8) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Slc22a7 in Genome Data Viewer
    Location:
    9q12
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (22044672..22052051)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (14547073..14554354)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (16925321..16931119)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Neighboring gene tau tubulin kinase 1 Neighboring gene cysteine-rich protein 3 Neighboring gene zinc finger protein 318 Neighboring gene small nucleolar RNA, H/ACA box 38 Neighboring gene uncharacterized LOC120094785

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in alpha-ketoglutarate transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in alpha-ketoglutarate transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in organic anion transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in organic anion transport TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in prostaglandin transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in prostaglandin transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in prostaglandin transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in response to stilbenoid ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in basal plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in basal plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in basolateral plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    solute carrier family 22 member 7
    Names
    Liver-specific transporter
    novel liver transporter
    organic anion transporter 2
    solute carrier family 22 (organic anion transporter), member 7

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053537.2NP_445989.2  solute carrier family 22 member 7

      See identical proteins and their annotated locations for NP_445989.2

      Status: PROVISIONAL

      Source sequence(s)
      AY816233
      UniProtKB/Swiss-Prot
      Q5RLM2, Q63314
      UniProtKB/TrEMBL
      A6JIQ9
      Related
      ENSRNOP00000025094.3, ENSRNOT00000025094.7
      Conserved Domains (2) summary
      cd06174
      Location:144511
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:11521
      2A0119; cation transport protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      22044672..22052051
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039084305.2XP_038940233.1  solute carrier family 22 member 7 isoform X2

      Conserved Domains (1) summary
      TIGR00898
      Location:1336
      2A0119; cation transport protein
    2. XM_039084304.2XP_038940232.1  solute carrier family 22 member 7 isoform X1

      Conserved Domains (1) summary
      TIGR00898
      Location:38427
      2A0119; cation transport protein