U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Tbcc tubulin folding cofactor C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316221, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tbccprovided by RGD
    Official Full Name
    tubulin folding cofactor Cprovided by RGD
    Primary source
    RGD:1306756
    See related
    AllianceGenome:RGD:1306756
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable GTPase activity. Predicted to be involved in post-chaperonin tubulin folding pathway and tubulin complex assembly. Predicted to be located in cytosol and photoreceptor connecting cilium. Predicted to be active in cytoplasm. Orthologous to human TBCC (tubulin folding cofactor C). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Tbcc in Genome Data Viewer
    Location:
    9q12
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (21596472..21597660, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (14098855..14100043, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (16405187..16406338, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene ubiquitin protein ligase E3 component n-recognin 2 Neighboring gene U6 spliceosomal RNA Neighboring gene peripherin 2 Neighboring gene BICRA like chromatin remodeling complex associated protein Neighboring gene uncharacterized LOC134480555 Neighboring gene small nucleolar RNA SNORA19 Neighboring gene ribosomal protein L7-like 1

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables tubulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in post-chaperonin tubulin folding pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in tubulin complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in photoreceptor connecting cilium ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    tubulin-specific chaperone C

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108200.3NP_001101670.1  tubulin-specific chaperone C

      See identical proteins and their annotated locations for NP_001101670.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      B2GUZ7, M0R7S2
      Conserved Domains (2) summary
      pfam07986
      Location:198315
      TBCC; Tubulin binding cofactor C
      pfam16752
      Location:26134
      TBCC_N; Tubulin-specific chaperone C N-terminal domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      21596472..21597660 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)