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    Slc25a29 solute carrier family 25 member 29 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314441, updated on 27-Nov-2024

    Summary

    Official Symbol
    Slc25a29provided by RGD
    Official Full Name
    solute carrier family 25 member 29provided by RGD
    Primary source
    RGD:1308104
    See related
    EnsemblRapid:ENSRNOG00000004351 AllianceGenome:RGD:1308104
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable acyl carnitine transmembrane transporter activity; high-affinity L-arginine transmembrane transporter activity; and high-affinity lysine transmembrane transporter activity. Predicted to be involved in L-alpha-amino acid transmembrane transport. Predicted to act upstream of or within acyl carnitine transmembrane transport and organic cation transport. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Orthologous to human SLC25A29 (solute carrier family 25 member 29). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 37.3), Heart (RPKM 32.7) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Slc25a29 in Genome Data Viewer
    Location:
    6q32
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (133506403..133517322, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (127742027..127752915, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (132736964..132747912, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120103621 Neighboring gene S-phase kinase-associated protein 1 pseudogene Neighboring gene YY1 transcription factor Neighboring gene uncharacterized LOC134479257 Neighboring gene microRNA 345 Neighboring gene solute carrier family 25, member 47

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables acyl carnitine transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    NOT enables acyl carnitine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables acyl carnitine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    NOT enables acyl carnitine transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables basic amino acid transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables basic amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables high-affinity L-arginine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables high-affinity L-arginine transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables high-affinity L-arginine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables high-affinity L-arginine transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables high-affinity lysine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables high-affinity lysine transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables high-affinity lysine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables high-affinity lysine transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in L-arginine transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in L-arginine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in L-arginine transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in L-histidine transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in L-histidine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in L-histidine transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in L-lysine transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in L-lysine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in L-lysine transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in acyl carnitine transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    NOT involved_in acyl carnitine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    NOT involved_in acyl carnitine transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within acyl carnitine transport ISO
    Inferred from Sequence Orthology
    more info
     
    NOT involved_in carnitine transport ISO
    Inferred from Sequence Orthology
    more info
     
    NOT involved_in carnitine transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitochondrial L-ornithine transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial L-ornithine transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitochondrial L-ornithine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial L-ornithine transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in ornithine transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ornithine transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    mitochondrial basic amino acids transporter
    Names
    carnitine/acylcarnitine translocase-like
    mitochondrial carnitine/acylcarnitine carrier protein CACL
    mitochondrial ornithine transporter 3
    solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
    solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001010958.1NP_001010958.1  mitochondrial basic amino acids transporter

      See identical proteins and their annotated locations for NP_001010958.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089065
      UniProtKB/Swiss-Prot
      Q5HZE0
      UniProtKB/TrEMBL
      A0A8I6GGF5, A6KBH5
      Related
      ENSRNOP00000005753.6, ENSRNOT00000005753.7
      Conserved Domains (2) summary
      PTZ00169
      Location:2259
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:88175
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      133506403..133517322 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039112402.2XP_038968330.1  mitochondrial basic amino acids transporter isoform X2

      UniProtKB/TrEMBL
      A0A8I6GGF5
      Related
      ENSRNOP00000111475.1, ENSRNOT00000145340.1
      Conserved Domains (1) summary
      pfam00153
      Location:60147
      Mito_carr; Mitochondrial carrier protein
    2. XM_006240541.5XP_006240603.1  mitochondrial basic amino acids transporter isoform X1

      UniProtKB/TrEMBL
      A0A8I6GGF5, A0A8L2Q298
      Conserved Domains (1) summary
      pfam00153
      Location:92179
      Mito_carr; Mitochondrial carrier protein