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    Jph4 junctophilin 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 445271, updated on 27-Nov-2024

    Summary

    Official Symbol
    Jph4provided by RGD
    Official Full Name
    junctophilin 4provided by RGD
    Primary source
    RGD:1303170
    See related
    EnsemblRapid:ENSRNOG00000025619 AllianceGenome:RGD:1303170
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in regulation of synaptic plasticity. Predicted to act upstream of or within several processes, including learning; neuromuscular process controlling balance; and regulation of store-operated calcium entry. Predicted to be located in dendritic shaft and smooth endoplasmic reticulum. Predicted to be part of junctional membrane complex. Predicted to be active in endoplasmic reticulum membrane and plasma membrane. Orthologous to human JPH4 (junctophilin 4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 143.9) See more
    Orthologs
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    Genomic context

    See Jph4 in Genome Data Viewer
    Location:
    15p13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (32549536..32558859, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (28579579..28588903, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (33767116..33777289, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134482119 Neighboring gene zinc finger homeobox 2 Neighboring gene thiamine triphosphatase Neighboring gene adaptor related protein complex 1 subunit gamma 2 Neighboring gene dehydrogenase/reductase member 2 like 1 Neighboring gene uncharacterized LOC120096987

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    junctophilin-4
    Names
    JP-4
    junctophilin-like 1 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003711.2NP_001003711.2  junctophilin-4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/Swiss-Prot
      Q69FB3
      UniProtKB/TrEMBL
      A6KGZ1
      Related
      ENSRNOP00000036180.5, ENSRNOT00000033977.8
      Conserved Domains (2) summary
      PLN03185
      Location:5143
      PLN03185; phosphatidylinositol phosphate kinase; Provisional
      PRK07003
      Location:369606
      PRK07003; DNA polymerase III subunit gamma/tau

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      32549536..32558859 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)