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    Entrep3 endosomal transmembrane epsin interactor 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310640, updated on 3-Dec-2024

    Summary

    Official Symbol
    Entrep3provided by RGD
    Official Full Name
    endosomal transmembrane epsin interactor 3provided by RGD
    Primary source
    RGD:1306107
    See related
    EnsemblRapid:ENSRNOG00000020518 AllianceGenome:RGD:1306107
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam189b; RGD1306107
    Summary
    Predicted to enable WW domain binding activity. Predicted to be located in membrane. Orthologous to human ENTREP3 (endosomal transmembrane epsin interactor 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 54.7), Spleen (RPKM 23.4) and 8 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Entrep3 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176886903..176893047)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (174588984..174595281)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (188495237..188501444)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene CDC-like kinase 2 Neighboring gene microRNA 3541 Neighboring gene secretory carrier membrane protein 3 Neighboring gene uncharacterized LOC102550011 Neighboring gene glucosylceramidase beta 1 Neighboring gene transfer RNA valine (anticodon AAC) 42

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables WW domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein ENTREP3
    Names
    family with sequence similarity 189, member B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107690.1NP_001101160.1  protein ENTREP3

      See identical proteins and their annotated locations for NP_001101160.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473976
      UniProtKB/TrEMBL
      A0A8I6ABH6, A6J6C5
      Conserved Domains (1) summary
      pfam04103
      Location:36196
      CD20; CD20-like family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      176886903..176893047
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039102316.2XP_038958244.1  protein ENTREP3 isoform X1

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:409637
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36200
      CD20; CD20-like family
    2. XM_039102317.2XP_038958245.1  protein ENTREP3 isoform X2

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:409636
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36200
      CD20; CD20-like family
    3. XM_039102322.2XP_038958250.1  protein ENTREP3 isoform X6

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:407625
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36200
      CD20; CD20-like family
    4. XM_039102323.2XP_038958251.1  protein ENTREP3 isoform X7

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:395623
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36200
      CD20; CD20-like family
    5. XM_008761169.4XP_008759391.1  protein ENTREP3 isoform X8

      UniProtKB/TrEMBL
      A0A8I6ABH6, D3Z8J6
      Conserved Domains (1) summary
      pfam04103
      Location:36200
      CD20; CD20-like family
    6. XM_063281847.1XP_063137917.1  protein ENTREP3 isoform X16

      UniProtKB/TrEMBL
      A0A8I6ABH6
    7. XM_039102318.2XP_038958246.1  protein ENTREP3 isoform X3

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:408636
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36200
      CD20; CD20-like family
    8. XM_039102324.2XP_038958252.1  protein ENTREP3 isoform X9

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:394622
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36200
      CD20; CD20-like family
    9. XM_017590886.3XP_017446375.1  protein ENTREP3 isoform X10

      UniProtKB/TrEMBL
      A0A8I6ABH6
    10. XM_063281848.1XP_063137918.1  protein ENTREP3 isoform X17

      UniProtKB/TrEMBL
      A0A8I6ABH6
    11. XM_039102319.2XP_038958247.1  protein ENTREP3 isoform X4

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:405633
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36196
      CD20; CD20-like family
    12. XM_063281845.1XP_063137915.1  protein ENTREP3 isoform X12

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Related
      ENSRNOP00000027828.8, ENSRNOT00000027828.9
    13. XM_006232664.4XP_006232726.1  protein ENTREP3 isoform X11

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (1) summary
      pfam04103
      Location:36196
      CD20; CD20-like family
    14. XM_063281849.1XP_063137919.1  protein ENTREP3 isoform X18

      UniProtKB/TrEMBL
      A0A8I6ABH6
    15. XM_039102320.2XP_038958248.1  protein ENTREP3 isoform X5

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:404632
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36196
      CD20; CD20-like family
    16. XM_063281846.1XP_063137916.1  protein ENTREP3 isoform X14

      UniProtKB/TrEMBL
      A0A8I6ABH6
    17. XM_063281851.1XP_063137921.1  protein ENTREP3 isoform X19

      UniProtKB/TrEMBL
      A0A8I6ABH6
    18. XM_039102328.2XP_038958256.1  protein ENTREP3 isoform X23

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:365593
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36156
      CD20; CD20-like family
    19. XM_063281855.1XP_063137925.1  protein ENTREP3 isoform X26

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Related
      ENSRNOP00000104427.1, ENSRNOT00000166647.1
    20. XM_063281856.1XP_063137926.1  protein ENTREP3 isoform X28

      UniProtKB/TrEMBL
      A0A8I6ABH6
    21. XM_039102329.2XP_038958257.1  protein ENTREP3 isoform X24

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:364592
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36156
      CD20; CD20-like family
    22. XM_039102325.2XP_038958253.1  protein ENTREP3 isoform X13

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:390618
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36181
      CD20; CD20-like family
    23. XM_039102326.2XP_038958254.1  protein ENTREP3 isoform X15

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:386614
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36177
      CD20; CD20-like family
    24. XM_063281852.1XP_063137922.1  protein ENTREP3 isoform X20

      UniProtKB/TrEMBL
      A0A8I6ABH6
    25. XM_039102327.2XP_038958255.1  protein ENTREP3 isoform X21

      UniProtKB/TrEMBL
      A0A8I6ABH6, A0A8I6GFC2
      Related
      ENSRNOP00000086795.2, ENSRNOT00000110005.2
      Conserved Domains (2) summary
      PHA03247
      Location:372599
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36177
      CD20; CD20-like family
    26. XM_063281853.1XP_063137923.1  protein ENTREP3 isoform X22

      UniProtKB/TrEMBL
      A0A8I6ABH6
    27. XM_063281854.1XP_063137924.1  protein ENTREP3 isoform X25

      UniProtKB/TrEMBL
      A0A8I6ABH6
    28. XM_039102330.2XP_038958258.1  protein ENTREP3 isoform X27

      UniProtKB/TrEMBL
      A0A8I6ABH6
      Conserved Domains (2) summary
      PHA03247
      Location:346574
      PHA03247; large tegument protein UL36; Provisional
      pfam04103
      Location:36137
      CD20; CD20-like family
    29. XM_063281857.1XP_063137927.1  protein ENTREP3 isoform X29

      UniProtKB/TrEMBL
      A0A8I6ABH6
    30. XM_063281858.1XP_063137928.1  protein ENTREP3 isoform X30

      UniProtKB/TrEMBL
      A0A8I6ABH6
    31. XM_039102332.2XP_038958260.1  protein ENTREP3 isoform X31

      Conserved Domains (1) summary
      PRK12323
      Location:231446
      PRK12323; DNA polymerase III subunit gamma/tau
    32. XM_063281859.1XP_063137929.1  protein ENTREP3 isoform X31

    33. XM_063281861.1XP_063137931.1  protein ENTREP3 isoform X33

    34. XM_063281862.1XP_063137932.1  protein ENTREP3 isoform X34

    35. XM_063281860.1XP_063137930.1  protein ENTREP3 isoform X32