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    Slc22a17 solute carrier family 22, member 17 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305886, updated on 27-Nov-2024

    Summary

    Official Symbol
    Slc22a17provided by RGD
    Official Full Name
    solute carrier family 22, member 17provided by RGD
    Primary source
    RGD:631405
    See related
    EnsemblRapid:ENSRNOG00000016414 AllianceGenome:RGD:631405
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Boct; 24p3R; rBOCT
    Summary
    Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in siderophore transport. Predicted to be located in organelle membrane and plasma membrane. Orthologous to human SLC22A17 (solute carrier family 22 member 17). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 700.7), Heart (RPKM 63.7) and 6 other tissues See more
    Orthologs
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    Genomic context

    See Slc22a17 in Genome Data Viewer
    Location:
    15p13
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (32352273..32358780, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (28382285..28389435, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (33569824..33576972, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene Bcl2-like 2 Neighboring gene poly(A) binding protein, nuclear 1 Neighboring gene embryonal Fyn-associated substrate Neighboring gene interleukin 25

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC116043

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables transmembrane signaling receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane signaling receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in siderophore transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in siderophore transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in organelle membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in organelle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in organelle membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in vacuolar membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    solute carrier family 22 member 17
    Names
    24p3 receptor
    brain-specific organic ion transporter
    brain-type organic cation transporter
    lipocalin-2 receptor
    solute carrier family 22 (organic cation transporter), member 17

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177421.3NP_803156.2  solute carrier family 22 member 17

      See identical proteins and their annotated locations for NP_803156.2

      Status: PROVISIONAL

      Source sequence(s)
      BC099072
      UniProtKB/Swiss-Prot
      Q4KLP1, Q9P290
      UniProtKB/TrEMBL
      A0A8I5ZZ20
      Related
      ENSRNOP00000096057.2, ENSRNOT00000104533.2
      Conserved Domains (2) summary
      cd06174
      Location:106476
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00893
      Location:111475
      2A0114; D-galactonate transporter

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      32352273..32358780 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006251965.2XP_006252027.1  solute carrier family 22 member 17 isoform X1

      See identical proteins and their annotated locations for XP_006252027.1

      UniProtKB/Swiss-Prot
      Q4KLP1, Q9P290
      UniProtKB/TrEMBL
      A0A8I5ZZ20
      Related
      ENSRNOP00000021851.6, ENSRNOT00000021851.8
      Conserved Domains (2) summary
      cd06174
      Location:106476
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00893
      Location:111475
      2A0114; D-galactonate transporter