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    SLN1 histidine kinase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854659, updated on 9-Dec-2024

    Summary

    Official Symbol
    SLN1
    Official Full Name
    histidine kinase
    Primary source
    SGD:S000001409
    Locus tag
    YIL147C
    See related
    AllianceGenome:SGD:S000001409; FungiDB:YIL147C; VEuPathDB:YIL147C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YPD2
    Summary
    Enables histidine phosphotransfer kinase activity; osmosensor activity; and protein histidine kinase activity. Involved in osmosensory signaling via phosphorelay pathway. Located in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See SLN1 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (69791..73453, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Mlp2p Neighboring gene ubiquitin-ribosomal 60S subunit protein L40A fusion protein Neighboring gene mitophagy protein ATG32 Neighboring gene pantoate--beta-alanine ligase PAN6

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding  
    enables histidine phosphotransfer kinase activity  
    enables histidine phosphotransfer kinase activity PubMed 
    enables histidine phosphotransfer kinase activity PubMed 
    enables kinase activity  
    enables metal ion binding  
    enables osmosensor activity PubMed 
    enables phosphorelay sensor kinase activity  
    enables phosphorelay sensor kinase activity  
    enables protein histidine kinase activity PubMed 
    Component Evidence Code Pubs
    located_in cell periphery PubMed 
    located_in membrane  
    is_active_in plasma membrane  
    located_in plasma membrane PubMed 
    located_in plasma membrane  

    General protein information

    Preferred Names
    histidine kinase
    NP_012119.1
    • Transmembrane histidine phosphotransfer kinase and osmosensor; regulates MAP kinase cascade; transmembrane protein with an intracellular kinase domain that signals to Ypd1p and Ssk1p, thereby forming a phosphorelay system similar to bacterial two-component regulators

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      69791..73453 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179495.1NP_012119.1  TPA: histidine kinase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012119.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVE0, P39928
      UniProtKB/TrEMBL
      B3LTZ4, C7GUR4
      Conserved Domains (2) summary
      PRK10935
      Location:518553
      PRK10935; nitrate/nitrite two-component system sensor histidine kinase NarQ
      PRK11107
      Location:5671210
      PRK11107; hybrid sensory histidine kinase BarA; Provisional
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