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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856540, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000001180
    Locus tag
    YHR138C
    See related
    AllianceGenome:SGD:S000001180; FungiDB:YHR138C; VEuPathDB:YHR138C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables endopeptidase inhibitor activity. Involved in vacuole fusion, non-autophagic. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (377355..377699, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Spl2p Neighboring gene aromatic-amino-acid:2-oxoglutarate transaminase Neighboring gene Sps100p Neighboring gene ncRNA Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LMA1 binds to vacuoles at Sec18p (NSF), transfers upon ATP hydrolysis to a t-SNARE (Vam3p) complex, and is released during fusion. Xu Z, et al. Cell, 1998 Jun 26. PMID 9657146
    2. Piezophysiology of genome wide gene expression levels in the yeast Saccharomyces cerevisiae. Iwahashi H, et al. Extremophiles, 2003 Aug. PMID 12910389
    3. Reconstitution and protein composition analysis of endocytic actin patches. Michelot A, et al. Curr Biol, 2010 Nov 9. PMID 21035341, Free PMC Article
    4. Yeast Saccharomyces cerevisiae adiponectin receptor homolog Izh2 is involved in the regulation of zinc, phospholipid and pH homeostasis. Mattiazzi Ušaj M, et al. Metallomics, 2015 Sep. PMID 26067383
    5. Annotating novel genes by integrating synthetic lethals and genomic information. Schöner D, et al. BMC Syst Biol, 2008 Jan 14. PMID 18194531, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables endopeptidase inhibitor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in vacuole fusion, non-autophagic IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vacuole fusion, non-autophagic IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_012006.1
    • hypothetical protein; similar to Pbi2p; double null mutant lacking Pbi2p and Yhr138cp exhibits highly fragmented vacuoles; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      377355..377699 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179268.1 → NP_012006.1  TPA: uncharacterized protein YHR138C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012006.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DL87, P38841
      UniProtKB/TrEMBL
      A6ZT46, B3LSQ2, C7GTW5, C8Z9T4, G2WFL1, N1P2V0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38841.1

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