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    SNR4 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 9164882, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SNR4
    Primary source
    SGD:S000006493
    Locus tag
    YNCE0019W
    See related
    AllianceGenome:SGD:S000006493
    Gene type
    ncRNA
    RNA name
    snoRNA
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables rRNA primary transcript binding activity and small ribosomal subunit rRNA binding activity. Involved in rRNA acetylation. Located in nucleolus. Part of box C/D methylation guide snoRNP complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SNR4 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (424698..424883)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Com2p Neighboring gene ribosomal 40S subunit protein S26B Neighboring gene Pmd1p Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yeast contains small nuclear RNAs encoded by single copy genes. Wise JA, et al. Cell, 1983 Dec. PMID 6197183
    2. A crucial RNA-binding lysine residue in the Nab3 RRM domain undergoes SET1 and SET3-responsive methylation. Lee KY, et al. Nucleic Acids Res, 2020 Apr 6. PMID 31960028, Free PMC Article
    3. A diverse set of nuclear RNAs transfer between nuclei of yeast heterokaryons. Olson BL, et al. Yeast, 2003 Jul 30. PMID 12868058
    4. A yeast small nuclear RNA is required for normal processing of pre-ribosomal RNA. Tollervey D. EMBO J, 1987 Dec 20. PMID 3327689, Free PMC Article
    5. Synthesis and assembly of the box C+D small nucleolar RNPs. Lafontaine DL, et al. Mol Cell Biol, 2000 Apr. PMID 10733567, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    • C/D box small nucleolar RNA (snoRNA); acts as antisense guide to target RNA base acetylation by Kre33p to cytosine 1280 in 18S rRNA (responsible for ac4C 1280); establishes extended bipartite complementarity around the cytosines targeted for acetylation, similar to pseudouridylation pocket formation by the H/ACA snoRNPs; base pairing between snR4 and 18S rRNA requires the putative helicase activity of Kre33p

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables rRNA primary transcript binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables small ribosomal subunit rRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in rRNA acetylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of box C/D methylation guide snoRNP complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of box C/D methylation guide snoRNP complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      424698..424883
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. NR_132169.1 RNA Sequence

      Status: REVIEWED

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