SPO71 Spo71p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: SPO71
Official Full Name: Spo71p
Primary source: SGD:S000002511
Locus tag: YDR104C
See related: AllianceGenome:SGD:S000002511; FungiDB:YDR104C; VEuPathDB:YDR104C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Involved in ascospore-type prospore membrane formation and protein localization to prospore membrane. Located in prospore membrane. [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome IV - NC_001136.10 Genomic Context describing neighboring genes

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SPO71 is required for the translocation of Vps13 from the endosome to the prospore membrane.
Title: SPO71 encodes a developmental stage-specific partner for Vps13 in Saccharomyces cerevisiae.
SPO71 plays a critical role in prospore membrane development.
Title: SPO71 mediates prospore membrane size and maturation in Saccharomyces cerevisiae.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in ascospore-type prospore membrane formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein localization to prospore membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein localization to prospore membrane	IDA Inferred from Direct Assay more info	PubMed
involved_in protein localization to prospore membrane	IEA Inferred from Electronic Annotation more info
involved_in sporulation resulting in formation of a cellular spore	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in prospore membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in prospore membrane	IDA Inferred from Direct Assay more info	PubMed
located_in prospore membrane	IEA Inferred from Electronic Annotation more info

NP_010389.3

Meiosis-specific protein required for prospore membrane morphogenesis; localizes to the prospore membrane (PSM) during sporulation; required for PSM elongation and closure; genetically antagonistic to SPO1; recruits Vps13p to the PSM during sporulation; interacts and functions cooperatively with Spo73p; mutants have defects in the PSM, aberrant spore wall formation and reduced PtdIns-phosphate pools in the PSM; contains three PH-like domains

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